Publication:
Analysis of FecB, BMP15 and CAMP gene mutations in sakiz sheep

dc.contributor.authorDincel, Deniz
dc.contributor.authorArdıçlı, Sena
dc.contributor.authorSoyudal, Bahadir
dc.contributor.authorEr, Mehlika
dc.contributor.authorAlpay, Fazlı
dc.contributor.authorŞamlı, Hale
dc.contributor.authorBalcı, Faruk
dc.contributor.buuauthorDİNÇEL, DENİZ
dc.contributor.buuauthorARDIÇLI, SENA
dc.contributor.buuauthorSoyudal, Bahadir
dc.contributor.buuauthorEr, Mehlika
dc.contributor.buuauthorALPAY, FAZLI
dc.contributor.buuauthorŞAMLI, HALE
dc.contributor.buuauthorBALCI, ÖMER FARUK
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi
dc.contributor.orcid0000-0002-8015-9032
dc.contributor.orcid0000-0003-2758-5945
dc.contributor.orcid0000-0003-2382-1330
dc.contributor.researcheridO-3394-2019
dc.contributor.researcheridAAE-4562-2019
dc.contributor.researcheridAAH-6488-2021
dc.contributor.researcheridAAH-6192-2021
dc.contributor.researcheridFXS-6181-2022
dc.contributor.researcheridCNK-1840-2022
dc.contributor.researcheridI-5009-2019
dc.date.accessioned2024-08-09T11:19:50Z
dc.date.available2024-08-09T11:19:50Z
dc.date.issued2015-07-01
dc.description.abstractFertility traits, such as the ovulation rate and the number of offspring at birth, are genetically regulated by fecundity genes. This study was performed to identify DNA polymorphisms in Booroola (FecB), Galway (FecX(G)), Inverdale (FecX(I)) and Calpastatin (CAST) genes in Sakiz sheep. A total of 71 ewes were genotyped for gene or allelic polymorphisms in the genes listed above using the PCR-RFLP method. The results obtained from this study indicated that all of the Sakiz ewes sampled were non-carriers for FecB, FecX(G) or FecX(I) mutations. However, genotypic frequencies in the CAST gene were 0.59, 0.36 and 0.05 for AA, AB and BB, respectively. A significant deviation from Hardy-Weinberg equilibrium for the CAST gene was not observed in the investigated breed (P>0.05). As a result, more extensive screening is required as tests for newly discovered mutations are developed. Additionally, this study is the first to report a genetic polymorphism in the CAST gene in Sakiz sheep.
dc.description.sponsorshipState Planning Organization - DPT-2005/2
dc.identifier.doi10.9775/kvfd.2014.12680
dc.identifier.endpage488
dc.identifier.issn1300-6045
dc.identifier.issue4
dc.identifier.startpage483
dc.identifier.urihttps://doi.org/10.9775/kvfd.2014.12680
dc.identifier.urihttps://hdl.handle.net/11452/43856
dc.identifier.volume21
dc.identifier.wos000354410800006
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherKafkas Üniversitesi Veteriner Fakültesi Dergisi
dc.relation.bapV-2004/4
dc.relation.journalKafkas Üniversitesi Veteriner Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIncreased ovulation rate
dc.subjectCalpastatin gene
dc.subjectFecundity genes
dc.subjectBooroola fecb
dc.subjectPcr-rflp
dc.subjectLitter size
dc.subjectPolymorphism
dc.subjectAssociation
dc.subjectBreeds
dc.subjectIb
dc.subjectSakiz sheep
dc.subjectFertility
dc.subjectFecb
dc.subjectBmp15
dc.subjectCast
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectVeterinary sciences
dc.titleAnalysis of FecB, BMP15 and CAMP gene mutations in sakiz sheep
dc.typeArticle
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoveryfba32adf-364c-47a8-a2bc-38b380bae0f6

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