Publication:
Qt dispersion in epileptic children and effect of antiepileptic drugs on QT dispersion

dc.contributor.authorŞentürk, Ebru Tayfun
dc.contributor.authorSemizel, Evren
dc.contributor.authorBostan, Özlem Mehtap
dc.contributor.authorOkan, Mehmet
dc.contributor.authorÇil, Ergün
dc.contributor.buuauthorTAYFUN ŞENTÜRK, EBRU
dc.contributor.buuauthorSemizel, Evren
dc.contributor.buuauthorBOSTAN, ÖZLEM MEHTAP
dc.contributor.buuauthorOKAN, MEHMET SAİT
dc.contributor.buuauthorÇİL, ERGÜN
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Kardiyoloji Anabilim Dalı.
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Nörolojisi Anabilim Dalı.
dc.contributor.orcid0000-0001-7707-2174
dc.contributor.orcid0000-0003-3516-0082
dc.contributor.researcheridJMN-6038-2023
dc.contributor.researcheridDQX-9595-2022
dc.contributor.researcheridAAG-8558-2021
dc.contributor.researcheridIMZ-1723-2023
dc.contributor.researcheridAAG-9324-2021
dc.date.accessioned2024-10-24T10:49:45Z
dc.date.available2024-10-24T10:49:45Z
dc.date.issued2010-09-01
dc.description.abstractPurpose: Sudden death in epileptic patients may due to epilepsia or drug induced arrhythmia. The aim of this study is to identify changes of QT dispersion, as a predictive marker for arrhythmias, in children treated with antiepileptic drugs.Material and Methods: Ninety children treated with antiepileptic drugs and 30 healthy children as controls were involved in the study. Standard 12-lead surface electrocardiograms (ECG) of the study groups were evaluated before antiepileptic drug therapy and after 3 months. ECG of the control group was also reviewed at the beginning of the study and after 3 months. QT, JT and RR intervals were measured in both groups. The corrected QT (QTc) and JT (JTc) intervals were determined and QTc and JTc dispersions were measured.Results: QTc and JTc dispersion were found to be 85.8+/-16.5 ms and 79.8+/-15.6 ms respectively in patients group before the therapy and 43.3+/-8.2 ms and 40.8+/-5.6 ms in control group at the beginning (p<0.05). Even QTc dispersion were found to be significantly decreased after 3 months of therapy (80.5+/-12.9 ms), it was still significantly higher than the QTc dispersion in control group after 3 months.Conclusion: Determination of QTcd and JTcd values may be useful to predict the risk of sudden death in epileptic patients.
dc.identifier.endpage194
dc.identifier.issn2149-2247
dc.identifier.issue3
dc.identifier.startpage189
dc.identifier.urihttps://jcpres.com/article/1510
dc.identifier.urihttps://hdl.handle.net/11452/47013
dc.identifier.volume32
dc.identifier.wos000421179400007
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherErciyes Üniversitesi Tıp Fakültesi
dc.relation.journalErciyes Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntiepileptic drugs
dc.subjectElectrocardiography
dc.subjectGeneral & internal medicine
dc.titleQt dispersion in epileptic children and effect of antiepileptic drugs on QT dispersion
dc.typeArticle
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoveryaaec1c8d-11f4-40c3-b09e-0b1465dccd66

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