Publication:
The role of white blood cell count in perianal pathologies: A retrospective analysis of hematologic malignancies

dc.contributor.authorOrhan, Bedrettin
dc.contributor.authorÖzkalemkaş, Fahir
dc.contributor.authorÖzkocaman, Vildan
dc.contributor.authorGürbüz, Büsra
dc.contributor.authorErsal, Tuba
dc.contributor.authorPınar, İbrahim Ethem
dc.contributor.authorYalçın, Cumali
dc.contributor.authorCandar, Ömer
dc.contributor.authorÇubukcu, Sinem
dc.contributor.authorKoca, Tuba Güllü
dc.contributor.authorAli, Rıdvan
dc.contributor.buuauthorORHAN, BEDRETTİN
dc.contributor.buuauthorÖZKALEMKAŞ, FAHİR
dc.contributor.buuauthorÖZKOCAMAN, VİLDAN
dc.contributor.buuauthorGÜRBÜZ, BÜŞRA
dc.contributor.buuauthorERSAL, TUBA
dc.contributor.buuauthorPINAR, İBRAHİM ETHEM
dc.contributor.buuauthorYALÇIN, CUMALİ
dc.contributor.buuauthorCANDAR, ÖMER
dc.contributor.buuauthorÇUBUKÇU, SİNEM
dc.contributor.buuauthorGÜLLÜ KOCA, TÛBA
dc.contributor.buuauthorALİ, RIDVAN
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Hematoloji Bilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.
dc.contributor.orcid0000-0001-9907-1498
dc.contributor.orcid0000-0003-4168-2821
dc.contributor.orcid0000-0002-5129-2977
dc.contributor.orcid0000-0002-5564-8862
dc.contributor.orcid0000-0001-7602-6926
dc.contributor.researcheridJWP-2738-2024
dc.contributor.researcheridACW-2157-2022
dc.contributor.researcheridGWQ-5007-2022
dc.contributor.researcheridKIE-5102-2024
dc.contributor.researcheridJGM-6601-2023
dc.contributor.researcheridGMY-8535-2022
dc.contributor.researcheridFQG-8981-2022
dc.contributor.researcheridJJB-0254-2023
dc.contributor.researcheridGWQ-5007-2022
dc.contributor.researcheridGXD-8209-2022
dc.contributor.researcheridAAJ-4354-2021
dc.date.accessioned2024-09-09T11:07:45Z
dc.date.available2024-09-09T11:07:45Z
dc.date.issued2022-07-01
dc.description.abstractBackground and Objective: Infections are the most common cause of anal and perianal pathologies in patients with hematological malignancies. Perianal infection diagnosis in this group of patients is difficult; thus, a careful anorectal examination is necessary with imaging modalities. In addition, the literature reveals a knowledge gap in the approach to anal pathologies in patients with neutropenia during diagnosis or chemotherapy. This study aimed to examine our institutional data on perianal complications and investigate the relationship between the white blood cell-neutrophil count, perianal lesion, and the type of treatment in patients with hematologic malignancies during the neutropenic period.Methods: Patients with a hematologic malignancy, hospitalized for cytotoxic chemotherapy, complicated by perianal pathology, documented by at least one imaging method, were included in the study.Results: A total of 42 patients were included in the study. Most of them had acute leukemia, 31 were affected by acute myeloid leukemia (AML), and 7 by Acute lymphoid leukemia (ALL). There was no statistically significant relationship between the anal abscess formation, the neutrophil count, and a previous perianal pathology. Anal abscess development was significantly more frequent in acute myeloid leukemia. An inverse relationship was found between the total white blood cell number at onset and having a surgical intervention for anal pathology.In conclusion, this article has shown that white blood cell count at the time of hospitalization can affect the surgical intervention in patients with hematological malignancy (in the majority with acute leukemia) affected by anal pathologies occurring in the neutropenic period.
dc.identifier.doi10.4084/MJHID.2022.051
dc.identifier.eissn2035-3006
dc.identifier.urihttps://doi.org/10.4084/MJHID.2022.051
dc.identifier.urihttps://www.mjhid.org/index.php/mjhid/article/view/4989
dc.identifier.urihttps://hdl.handle.net/11452/44408
dc.identifier.volume14
dc.identifier.wos000818865900006
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherMattioli 1885
dc.relation.journalMediterranean Journal of Hematology and Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInfections
dc.subjectManagement
dc.subjectLeukemia
dc.subjectPerianal
dc.subjectAcute leukemia
dc.subjectWhite blood cell
dc.subjectHematology
dc.subjectInfectious diseases
dc.titleThe role of white blood cell count in perianal pathologies: A retrospective analysis of hematologic malignancies
dc.typeArticle
dspace.entity.typePublication
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