Publication:
Assessment of health-related quality of life in pediatric acute lymphoblastic leukemia survivors: Perceptions of children, siblings, and parents

dc.contributor.authorKızmazoğlu, Deniz
dc.contributor.authorSarı, Seher
dc.contributor.authorTüfekçi, Özlem
dc.contributor.authorYenigürbüz, Fatma Demir
dc.contributor.authorYılmaz, Şebnem
dc.contributor.authorÖren, Hale
dc.contributor.buuauthorSezgin, Melike Evim
dc.contributor.buuauthorKantarcıoğlu, Arzu
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri/Çocuk Sağlığı Ve Hastalıkları Bölümü
dc.contributor.researcheridDRM-9969-2022
dc.contributor.researcheridILH-2286-2023
dc.contributor.researcheridDVW-8108-2022
dc.contributor.researcheridJGX-6145-2023
dc.contributor.scopusid57208701966
dc.contributor.scopusid55317096200
dc.contributor.scopusid6506622162
dc.contributor.scopusid24072843300
dc.date.accessioned2024-05-21T09:51:49Z
dc.date.available2024-05-21T09:51:49Z
dc.date.issued2019
dc.description.abstractObjective: We investigated the health-related quality of life (HRQL) in survivors of pediatric acute lymphoblastic leukemia (ALL) and evaluated the perceptions of the children, their siblings, and their parents. Materials and Methods: Seventy ALL survivors, who were between 7 and 17 years of age and had completed therapy ≥2 years, were included. The control group consisted of their healthy siblings. HRQL was assessed by the age-specific KINDLR questionnaire. Results: No significant differences could be found among HRQL scores of ALL survivors with respect to variables such as sex, risk group, and having chronic illness. HRQL scores for physical well-being, emotional well-being, family, and social functioning of the patient and sibling self-reports and parent proxy reports were lower than the expected values for healthy and chronically ill children. Conclusion: These results demonstrate that both ALL survivors and their families need help via psychological counseling programs to improve their HRQL even after completion of therapy. Keywords: Acute lymphoblastic leukemia, Health-related quality of life, KINDLR questionnaire
dc.description.abstractAmaç: Çocukluk çağı akut lenfoblastik lösemi (ALL) sağ kalanlarında sağlıkla ilişkili yaşam kalitesinin (HRQL) araştırılması ve çocukların, kardeşlerinin ve ebeveynlerinin bununla ilgili algılamalarının değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Çalışma grubu 7-17 yaş arası, kemoterapisi en az 2 yıl önce tamamlanmış 70 ALL’li çocuktan oluşturuldu. Kontrol grubu hastaların sağlıklı kardeşlerini (n=32) içerdi. HRQL ölçümü için yaşa uygun KINDLR anket formları kullanıldı. Bulgular: ALL sağ kalanlarında HRQL skorları cinsiyet, risk grubu, kronik hastalığı olma ve relaps öyküsü açısından istatistiksel anlamlı fark göstermedi. Hastalar ve kardeşlerinin HRQL skorlarıyla ebeveynlerin hasta çocuklarının durumuna bakış açısı skorları değerlendirildiğinde fiziksel iyilik, duygusal iyilik, aile ve sosyal ilişkiler ile ilgili HRQL skorları sağlıklı ve kronik hastalığa sahip çocuklara göre düşük bulundu. Sonuç: Hasta ve ebeveynlerin HRQL skorlarının düşük saptanması çocukluk çağı ALL sağ kalanları ve ebeveynlerinin tedavi bitimi sonrasında da psikolojik danışmanlık programlarına ihtiyacı olduğunu göstermektedir.
dc.identifier.endpage116
dc.identifier.issn1300-7777
dc.identifier.issn1308-5263
dc.identifier.issue36
dc.identifier.pubmed30401658
dc.identifier.scopus2-s2.0-85065570457
dc.identifier.startpage112
dc.identifier.urihttps://doi.org/10.4274/tjh.galenos.2018.2018.0351
dc.identifier.urihttps://jag.journalagent.com/tjh/pdfs/TJH_36_2_112_116.pdf
dc.identifier.urihttps://hdl.handle.net/11452/41506
dc.identifier.volume2
dc.identifier.wos000466766800006
dc.indexed.pubmedPubMed
dc.indexed.scopusScopus
dc.indexed.trdizinTRDizin
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherGalenos Publishing House
dc.relation.collaborationYurt içi
dc.relation.journalTurkish Journal of Hematology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHematology
dc.subjectAcute lymphoblastic leukemia
dc.subjectHealth-related quality of life
dc.subjectKindlr questionnaire
dc.subjectLong-term survivors
dc.subjectChildhood-cancer
dc.subjectDepression
dc.subjectTherapy
dc.subjectQuestionnaire
dc.subjectAdolescents
dc.subjectDiagnosis
dc.subjectGermany
dc.subjectAnxiety
dc.subject.emtreeAcute lymphoblastic leukemia
dc.subject.emtreeAdolescent
dc.subject.emtreeCancer survivor
dc.subject.emtreeChild
dc.subject.emtreeChild parent relation
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeMale
dc.subject.emtreePsychology
dc.subject.emtreeQuality of life
dc.subject.emtreeQuestionnaire
dc.subject.emtreeSibling
dc.subject.meshAdolescent
dc.subject.meshCancer survivors
dc.subject.meshChild
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshParents
dc.subject.meshPrecursor cell lymphoblastic leukemia-lymphoma
dc.subject.meshQuality of life
dc.subject.meshSiblings
dc.subject.meshSurveys and questionnaires
dc.subject.scopusStandardized Nursing Terminology; Nursing Diagnosis; Nurses
dc.subject.wosHematology
dc.titleAssessment of health-related quality of life in pediatric acute lymphoblastic leukemia survivors: Perceptions of children, siblings, and parents
dc.typeArticle
dspace.entity.typePublication

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