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Three dimensional development and asymmetry of the corpus callosum in the 0-18 age group: A retrospective magnetic resonance imaging study

dc.contributor.authorIşıklar, Sefa
dc.contributor.authorÖzdemir, Senem Turan
dc.contributor.authorÖzkaya, Güven
dc.contributor.authorÖzpar, Rıfat
dc.contributor.buuauthorIŞIKLAR, SEFA
dc.contributor.buuauthorÖzdemir, Senem Turan
dc.contributor.buuauthorÖZKAYA, GÜVEN
dc.contributor.buuauthorÖZPAR, RİFAT
dc.contributor.departmentBursa Uludağ Üniversitesi/Sağlık Hizmetleri Meslek Yüksekokulu/Tıbbi Görüntüleme Teknikleri Programı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Anatomi Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Bölümü Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.
dc.contributor.orcid0000-0002-2070-5193
dc.contributor.orcid0000-0003-0297-846X
dc.contributor.orcid0000-0001-6649-9287
dc.contributor.researcheridAAK-3779-2021
dc.contributor.researcheridA-4421-2016
dc.contributor.researcheridAAH-5062-2021
dc.contributor.researcheridFPU-9468-2022
dc.date.accessioned2024-09-27T05:55:26Z
dc.date.available2024-09-27T05:55:26Z
dc.date.issued2022-12-26
dc.description.abstractMost of the corpus callosum (CC) developmental studies are concerned with its two-dimensional structure. Linear and area measurements do not directly assess the CC size but estimate the overall structure from the cross-sectional image. This study investigated age- and sex-related changes in volumetric development and asymmetry of CC from birth to 18. For this retrospective study, we selected 696 patients (329 [47.27%] females) with both 3D-T1-weighted sequence and normal radiological anatomy from patients 0-18 years of age who had brain magnetic resonance imaging (MRI) between 2012 and 2020. The genu, body, splenium, and total volume of CC were calculated using MRICloud. The measurement results of 23 age groups were analyzed with SPSS (ver.28). Total CC volume was 18740.76 +/- 4314.06 mm(3) between 0 and 18 years of age, and its ratio to total brain volume (TBV) was 1.70% +/- 0.23%. We observed that the total CC volume has six developmental periods 0 years, 1, 2-4, 5-9, 10-16, and 17-18 years. Genu and body grew in five developmental periods, while splenium in seven. There was intermittent sexual dimorphism in the CC volume in the first 4 years of life (p < 0.05). However, sex factor was insignificant in CC ratio to TBV. Total CC was right lateralized on average 1.81% (ranging -0.59% to 4.52%). Genu was 8.70% lateralized to the right, the body was 2.99% to the left, and the splenium was 1.41% to the right. The three-dimensional development of CC agreed with the two-dimensional developmental data of CC except for some differences.
dc.identifier.doi10.1002/ca.23996
dc.identifier.endpage598
dc.identifier.issn0897-3806
dc.identifier.issue4
dc.identifier.startpage581
dc.identifier.urihttps://doi.org/10.1002/ca.23996
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/ca.23996
dc.identifier.urihttps://hdl.handle.net/11452/45359
dc.identifier.volume36
dc.identifier.wos000903737600001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherWiley
dc.relation.journalClinical Anatomy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectWhite-matter microstructure
dc.subjectNervous-system myelination
dc.subjectHemispheric-asymmetry
dc.subjectSex-differences
dc.subjectInterhemispheric-transfer
dc.subjectProjection neurons
dc.subjectAlzheimers-disease
dc.subjectFiber composition
dc.subjectHuman infancy
dc.subjectMorphology
dc.subject3-d imaging
dc.subjectAnatomy
dc.subjectCorpus callosum
dc.subjectDevelopment
dc.subjectMagnetic resonance imaging
dc.subjectPediatrics
dc.subjectAnatomy & morphology
dc.titleThree dimensional development and asymmetry of the corpus callosum in the 0-18 age group: A retrospective magnetic resonance imaging study
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication8183356b-fb17-47f9-86d8-9566fdeb85ab
relation.isAuthorOfPublication648e85b9-2f4f-4f92-a2d7-794286abd0fd
relation.isAuthorOfPublication597eca82-1312-4286-b1b1-b47aec03619c
relation.isAuthorOfPublication.latestForDiscovery8183356b-fb17-47f9-86d8-9566fdeb85ab

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