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Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea

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dc.contributor.buuauthorEryılmaz, Salih
dc.contributor.buuauthorAydınlar, Ali
dc.contributor.buuauthorŞentürk, Tunay
dc.contributor.buuauthorUrsavaş, Ahmet
dc.contributor.buuauthorAydın, Aysel Kaderli
dc.contributor.buuauthorÖzdemir, Bülent
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentGöğüs Hastalıkları Ana Bilim Dalı
dc.contributor.departmentKardiyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-8974-8837
dc.contributor.researcheridAAI-3169-2021
dc.contributor.researcheridAAI-6632-2021
dc.contributor.researcheridC-1517-2017
dc.contributor.scopusid37037269800
dc.contributor.scopusid6603131517
dc.contributor.scopusid8342098300
dc.contributor.scopusid8329319900
dc.contributor.scopusid36460564300
dc.contributor.scopusid7004168959
dc.date.accessioned2022-07-04T10:11:01Z
dc.date.available2022-07-04T10:11:01Z
dc.date.issued2010-10
dc.description.abstractBackground: Reduced arterial elasticity is an important mediator of accelerated atherogenesis and consequent increased cardiovascular morbidity in obstructive sleep apnea (OSA). The aim of our study was to investigate whether continuous positive airway pressure (CPAP) therapy may improve arterial elasticity in subjects with OSA. Methods: In 44 subjects with OSA, we measured arterial elasticity by applanation tonometry before and after 6 months of treatment with CPAP. Nine OSA+ subjects withdrew from the study. Results: The 35 patients with OSA who completed the 6-month CPAP treatment showed a marked reduction in both the large artery (LAEI, P = 0.001) and small artery (SAEI, P = 0.009) elasticity indices, independent of potential confounders. In OSA+ subjects who withdrew from the study, SAEI and LAEI did not change significantly over time. Conclusions: Six months of CPAP therapy improves arterial elasticity in subjects with OSA.
dc.identifier.citationEryılmaz, S. vd. (2010). "Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea". Respiratory Medicine, 104(10), 1571-1576.
dc.identifier.endpage1576
dc.identifier.issn0954-6111
dc.identifier.issn1532-3064
dc.identifier.issue10
dc.identifier.pubmed20570124
dc.identifier.scopus2-s2.0-77956340887
dc.identifier.startpage1571
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2010.05.002
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0954611110002167
dc.identifier.urihttp://hdl.handle.net/11452/27648
dc.identifier.volume104
dc.identifier.wos000282247300024
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherW B Saunders CO
dc.relation.journalRespiratory Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectObstructive sleep apnea syndrome
dc.subjectEndothelial dysfunction
dc.subjectArterial elasticity
dc.subjectContinuous positive airway pressure
dc.subjectPulse-wave velocity
dc.subjectEndothelial dysfunction
dc.subjectNitric-oxide
dc.subjectStiffness
dc.subjectAtherosclerosis
dc.subjectAssociation
dc.subjectModerate
dc.subjectCPAP
dc.subjectCardiovascular system & cardiology
dc.subjectRespiratory system
dc.subject.emtreeArtery elasticity
dc.subject.emtreeArticle
dc.subject.emtreeCardiovascular risk
dc.subject.emtreeClinical article
dc.subject.emtreeElasticity
dc.subject.emtreeHuman
dc.subject.emtreePositive end expiratory pressure
dc.subject.emtreePriority journal
dc.subject.emtreeSleep apnea syndrome
dc.subject.emtreeTherapy effect
dc.subject.meshArteries
dc.subject.meshContinuous positive airway pressure
dc.subject.meshElasticity
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshPolysomnography
dc.subject.meshSleep apnea, obstructive
dc.subject.meshTime factors
dc.subject.meshTreatment outcome
dc.subject.scopusObstructive Sleep Apnea; Positive End Expiratory Pressure; Pressure Treatment
dc.subject.wosCardiac & cardiovascular systems
dc.subject.wosRespiratory system
dc.titleContinuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Kardiyoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Göğüs Hastalıkları Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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