Publication:
Dose dependent effects of spirulina platensis on liver health in rats

dc.contributor.authorSeyidoglu, Nilay
dc.contributor.authorİnan, Sevda
dc.contributor.buuauthorGüneş, Nazmiye
dc.contributor.buuauthorGÜNEŞ, NAZMİYE
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/Biyokimya Anabilim Dalı.
dc.contributor.researcheridAAI-1930-2021
dc.date.accessioned2024-07-04T12:02:12Z
dc.date.available2024-07-04T12:02:12Z
dc.date.issued2020-03-01
dc.description.abstractSpirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study's aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats're used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely.
dc.description.sponsorshipResearch Foundations of Namik Kemal University - - NKUBAP.10 16.074
dc.identifier.doi10.18805/ijar.B-1055
dc.identifier.endpage353
dc.identifier.issn0367-6722
dc.identifier.issue3
dc.identifier.startpage349
dc.identifier.urihttps://doi.org/10.18805/ijar.B-1055
dc.identifier.urihttps://hdl.handle.net/11452/42909
dc.identifier.volume54
dc.identifier.wos000522456700015
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherAgricultural Research Communication Centre
dc.relation.journalIndian Journal Of Animal Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiochemical parameters
dc.subjectDouble-blind
dc.subjectObesity
dc.subjectManagement
dc.subjectWeight
dc.subjectBody condition
dc.subjectCholesterol
dc.subjectLiver health
dc.subjectMicroalgae
dc.subjectSpirulina platensis
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectAgriculture, dairy & animal science
dc.subjectAgriculture
dc.titleDose dependent effects of spirulina platensis on liver health in rats
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication24c30b5c-e024-4541-9a91-ab2627c5266a
relation.isAuthorOfPublication.latestForDiscovery24c30b5c-e024-4541-9a91-ab2627c5266a

Files

Collections