Publication:
Synergistic effect of feed additives on cell proliferation and morphology in quail (coturnix coturnix japonica) duodenum

dc.contributor.buuauthorYEŞİLBAĞ, DERYA
dc.contributor.buuauthorAsmaz, Ender Deniz
dc.contributor.buuauthorYeşilbağ, Derya
dc.contributor.buuauthorOdabası, F.
dc.contributor.buuauthorZık, Berrin
dc.contributor.buuauthorZIK, BERRİN
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/Histoloji ve Embriyoloji Anabilim Dalı.
dc.contributor.researcheridAAH-9810-2021
dc.contributor.researcheridHPG-0648-2023
dc.date.accessioned2024-10-04T08:08:22Z
dc.date.available2024-10-04T08:08:22Z
dc.date.issued2022-07-01
dc.description.abstractThe present study aimed to investigate the effect of a commercial probiotic and a commercial essential oil blend and their mixture, as a natural feed additive, on the expression level of Proliferating Cell Nuclear Antigen (PCNA), proliferation index (PI), and total mucosal thickness of quails. 1-day-old Japanese (Coturnix coturnix Japon-ica) quails, including both males and females, were divided into four groups as follows: (1) control treatment without medication (n: 15); (2) 18 g/ ton-1 probiotic (n: 15); (3) 300 g/ ton-1 essential oil blend (n: 15) and (4) 18 g/ ton-1 probiotic plus 300 g/ ton-1 essential oil blend (n: 15). The study evaluated the effect of natural feed additives added to the quail diet on intestinal health by immunohistochemical and histological analysis. At the end of the experiment, the quail's duodenum was removed, fixed in 10% neutral buffered formalin, and performed a histological examination.As a result of the study, it was determined that the PCNA expressions, proliferation index, and mucosal thickness were generally significantly increased in the experimental groups compared to the control group (P<0.001). The combina-tion of additives caused a synergistic effect for this study. All data were statistically significant in the group where the probiotic and essential oil mixture was used together. It has been determined that these feed additives combination stimulates cell proliferation in the duodenum, where nutrients are absorbed and positively affect intestinal morphology.
dc.identifier.doi10.12681/jhvms.27850
dc.identifier.endpage4582
dc.identifier.issn1792-2720
dc.identifier.issue3
dc.identifier.startpage4575
dc.identifier.urihttps://doi.org/10.12681/jhvms.27850
dc.identifier.urihttps://hdl.handle.net/11452/45851
dc.identifier.volume73
dc.identifier.wos000883361900002
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherHellenic Veterinary Medical Soc
dc.relation.journalJournal Of The Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIntestinal stem-cells
dc.subjectGrowth-performance
dc.subjectBroiler-chickens
dc.subjectImmune-response
dc.subjectEssential oil
dc.subjectBenzoic-acid
dc.subjectMeat quality
dc.subjectMicroflora
dc.subjectSupplementation
dc.subjectHistomorphology
dc.subjectDuodenum
dc.subjectEssential oil blend
dc.subjectPcna
dc.subjectProbiotic
dc.subjectQuails
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectVeterinary sciences
dc.titleSynergistic effect of feed additives on cell proliferation and morphology in quail (coturnix coturnix japonica) duodenum
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication0ec8c7dc-1c1b-4d07-9219-d9dc20d81cc1
relation.isAuthorOfPublicationa30427a9-dc3b-4196-927b-d5b5b4e35e1f
relation.isAuthorOfPublication.latestForDiscoverya30427a9-dc3b-4196-927b-d5b5b4e35e1f

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