Publication:
Serum fetuin-A levels in patients with systolic heart failure

dc.contributor.buuauthorKeçebaş, Mesut
dc.contributor.buuauthorGüllülü, Sümeyye
dc.contributor.buuauthorSaǧ, Saim
dc.contributor.buuauthorBeşli, Feyzullah
dc.contributor.buuauthorAçıkgöz, Ebru
dc.contributor.buuauthorSarandöl, Emre
dc.contributor.buuauthorAydınlar, Ali Altun
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-2593-7196tr_TR
dc.contributor.orcid0000-0001-8404-8252tr_TR
dc.contributor.orcid0000-0002-8974-8837tr_TR
dc.contributor.researcheridABE-1716-2020tr_TR
dc.contributor.researcheridAAW-9185-2020tr_TR
dc.contributor.researcheridAAI-6632-2021tr_TR
dc.contributor.scopusid36198369900tr_TR
dc.contributor.scopusid57204660708tr_TR
dc.contributor.scopusid12140008100tr_TR
dc.contributor.scopusid35767335000tr_TR
dc.contributor.scopusid56328183700tr_TR
dc.contributor.scopusid55943324800tr_TR
dc.contributor.scopusid6603131517tr_TR
dc.date.accessioned2024-02-26T11:04:44Z
dc.date.available2024-02-26T11:04:44Z
dc.date.issued2014-05-05
dc.description.abstractObjective Inflammation and dystrophic calcification have been associated with cardiovascular disease (CVD) and chronic heart failure (CHF). The aim of the present study was to investigate the potential usefulness of fetuin-A as a biomarker in CHF. Methods Serum fetuin-A was measured in 66 CHF patients with left ventricular function < 50% and in 31 healthy controls at baseline. Fetuin-A was evaluated as a diagnostic marker for systolic heart failure and compared with C-reactive protein (CRP) and pro-brain natriuretic peptide (pro-BNP). Results The levels of serum fetuin-A were significantly decreased in the CHF patients compared to the control group (P < 0.01). Although there were significant correlations between fetuin-A and certain parameters in patients and controls, none of these were present consistently in either group. It was found that serum fetuin-A levels could identify patients with systolic heart failure with a high degree of sensitivity and specificity. Conclusions Serum fetuin-A is decreased in CHF patients, indicating that anti-inflammatory activity is downregulated in CHF and that calcification may be associated with CHF.en_US
dc.identifier.citationKeçebaş, M. vd. (2014). "Serum fetuin-A levels in patients with systolic heart failure". Acta Cardiologica, 69(4), 399-405.en_US
dc.identifier.doihttps://doi.org/10.2143/AC.69.4.3036656en_US
dc.identifier.eissn1784-973X
dc.identifier.endpage405tr_TR
dc.identifier.issn0001-5385
dc.identifier.issue4tr_TR
dc.identifier.pubmed25181915tr_TR
dc.identifier.scopus2-s2.0-84906089008tr_TR
dc.identifier.startpage399tr_TR
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/AC.69.4.3036656en_US
dc.identifier.urihttps://hdl.handle.net/11452/39966en_US
dc.identifier.volume69tr_TR
dc.identifier.wos000346681400007
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.journalActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic heart failureen_US
dc.subjectInflammationen_US
dc.subjectFetuin-Aen_US
dc.subjectAlpha(2)-heremans-schmid glycoprotein/fetuin-aen_US
dc.subjectDiastolic dysfunctionen_US
dc.subjectMechanismsen_US
dc.subjectInsulin-resistanceen_US
dc.subjectAccumulationen_US
dc.subjectHs-glycoproteinen_US
dc.subjectExpressionen_US
dc.subjectCalcificationen_US
dc.subjectAssociationen_US
dc.subjectCardiovascular system & cardiologyen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAntiinflammatory activityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBlood examinationen_US
dc.subject.emtreeBlood pressureen_US
dc.subject.emtreeCardiomyopathyen_US
dc.subject.emtreeCardiovascular parametersen_US
dc.subject.emtreeCongestive heart failureen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCreatinine blood levelen_US
dc.subject.emtreeDiagnostic test accuracy studyen_US
dc.subject.emtreeDisease markeren_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeEchocardiographyen_US
dc.subject.emtreeEnd diastolic diameteren_US
dc.subject.emtreeEnd systolic diameteren_US
dc.subject.emtreeEnzyme linked immunosorbent assayen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGlomerulus filtration rateen_US
dc.subject.emtreeHeart left ventricle ejection fractionen_US
dc.subject.emtreeHeart left ventricle functionen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeIschemic heart diseaseen_US
dc.subject.emtreeKidney diseaseen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeNew york heart association classen_US
dc.subject.emtreeReceiver operating characteristicen_US
dc.subject.emtreeSensitivity and specificityen_US
dc.subject.emtreeSystolic heart failureen_US
dc.subject.emtreeThorax radiographyen_US
dc.subject.emtreeAcetylsalicylic aciden_US
dc.subject.emtreeAngiotensin 2 receptor antagonisten_US
dc.subject.emtreeBrain natriuretic peptideen_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeCalcium channel blocking agenten_US
dc.subject.emtreeDigitoxinen_US
dc.subject.emtreeDipeptidyl carboxypeptidase inhibitoren_US
dc.subject.emtreeFetuin aen_US
dc.subject.emtreeFurosemideen_US
dc.subject.emtreeHemoglobinen_US
dc.subject.emtreeHigh density lipoproteinen_US
dc.subject.emtreeHydroxymethylglutaryl coenzyme a reductase inhibitoren_US
dc.subject.emtreeLow density lipoproteinen_US
dc.subject.emtreeNitric acid derivativeen_US
dc.subject.emtreeSpironolactoneen_US
dc.subject.emtreeTriacylglycerolen_US
dc.subject.meshAgeden_US
dc.subject.meshAlpha-2-hs-glycoproteinen_US
dc.subject.meshBiological markersen_US
dc.subject.meshC-reactive proteinen_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart failure, systolicen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNatriuretic peptide, brainen_US
dc.subject.meshPeptide fragmentsen_US
dc.subject.meshPredictive value of testsen_US
dc.subject.meshSensitivity and specificityen_US
dc.subject.meshSeverity of illness indexen_US
dc.subject.meshVentricular dysfunction, leften_US
dc.subject.scopusFetuin A; Glycoprotein; Human AHSG Proteinen_US
dc.subject.wosCardiac & cardiovascular systemsen_US
dc.titleSerum fetuin-A levels in patients with systolic heart failureen_US
dc.typeArticleen_US
dc.wos.quartileQ4 (Cardiac & Cardiovascular Systems)en_US
dspace.entity.typePublication

Files

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:

Collections