Publication:
Viral and atypical bacterial respiratory infections in a university teaching hospital

dc.contributor.authorHarun, Ağca
dc.contributor.authorBeyza, Ener
dc.contributor.buuauthorAĞCA, HARUN
dc.contributor.buuauthorENER, BEYZA
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Mikrobiyoloji Anabilim Dalı
dc.contributor.orcid0000-0002-2651-2034
dc.contributor.researcheridAAH-4027-2021
dc.contributor.researcheridISU-9626-2023
dc.date.accessioned2024-07-16T06:12:50Z
dc.date.available2024-07-16T06:12:50Z
dc.date.issued2019-09-01
dc.description.abstractRespiratory viral and atypical bacterial agents lead to infections in a large spectrum, from mild symptoms to respiratory failure. In the present study, we aimed to detect multiple viral and bacterial agents in the respiratory samples of inpatients by real-time polymerase chain reaction (RT-PCR). Nasopharyngeal swabs and broncho-alveolar lavage samples from inpatients with respiratory infection symptoms at the Uludag University Hospital between December 1, 2015 and March 31,2018 were investigated. DNA/RNA was extracted using the EZ1 Virus Mini Kit v2.0 (Qiagen, Belgium) with the EZ1 extraction device (Qiagen, Belgium). The R-GENE (R) RT-PCR (Biomerioux, France) kit was used to detect influenza A, influenza B, respiratory syncytial virus (RSV), human metapneumovirus, rhinovirus/enterovirus (RV/EV), adenovirus, human bocavirus (hBoV), corona virus, parainfluenza virus, Chlamydia pneumoniae/Mycoplasma pneumoniae, and Legionella pneumophila in Rotor-Gene Q (Qiagen, Belgium). Patients were aged between 0 and 90 years. Overall, 177 (56.9%) patients were men and 134 (43.1%) were women. A total of 311 samples were analyzed, of which 214 (68.8%) were positive. In total, 360 agents, including 338 viruses and 22 bacteria, were detected. The commonest agents were influenza A+B (n = 65, 18,1%), hBoV (n = 64, 17.8%), RV/EV (n = 56, 15.6%), and RSV (n = 47, 13.1%). Rapid diagnosis of viral infections by RT-PCR is important for the specific treatment of patients.
dc.identifier.doi10.7883/yoken.JJID.2018.510
dc.identifier.eissn1884-2836
dc.identifier.endpage322
dc.identifier.issn1344-6304
dc.identifier.issue5
dc.identifier.startpage318
dc.identifier.urihttps://doi.org/10.7883/yoken.JJID.2018.510
dc.identifier.urihttps://www.jstage.jst.go.jp/article/yoken/72/5/72_JJID.2018.510/_article
dc.identifier.urihttps://hdl.handle.net/11452/43277
dc.identifier.volume72
dc.identifier.wos000489677000006
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherNatl Inst Infectious Diseases
dc.relation.journalJapanese Journal of Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectStem-cell transplantation
dc.subjectReal-time pcr
dc.subjectEnterovirus d68
dc.subjectHuman bocavirus
dc.subjectRhinovirus
dc.subjectPneumonia
dc.subjectOutpatients
dc.subjectMortality
dc.subjectInfluenza
dc.subjectDiagnosis
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectInfectious diseases
dc.titleViral and atypical bacterial respiratory infections in a university teaching hospital
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublicationeeb102e3-a297-417f-962b-8b6991f5b89b
relation.isAuthorOfPublication2b082cc1-092b-441d-bafb-e08676bd66bb
relation.isAuthorOfPublication.latestForDiscoveryeeb102e3-a297-417f-962b-8b6991f5b89b

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