Publication:
Detecting fecal egg count (FEC) for gastrointestinal nematodes of adult Turkish sheep with different scrapie related PRNP haplotypes

dc.contributor.authorYaman, Yalçın
dc.contributor.authorŞenlik, Bayram
dc.contributor.authorÖzuiçli, Mehmet
dc.contributor.authorKeleş, Murat
dc.contributor.authorAymaz, Ramazan
dc.contributor.authorBay, Veysel
dc.contributor.authorHatipoğlu, Ecem
dc.contributor.authorKoncagül, Seyrani
dc.contributor.authorÖner, Yasemin
dc.contributor.authorÜn, Cemal
dc.contributor.buuauthorŞENLİK, BAYRAM
dc.contributor.buuauthorÖZÜİÇLİ, MEHMET
dc.contributor.buuauthorÖNER, YASEMİN
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/Parazitoloji Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Ziraat Fakültesi/Biyometri ve Genetik Bölümü.
dc.contributor.researcheridGBN-0139-2022
dc.contributor.researcheridJIF-7199-2023
dc.contributor.researcheridABB-3181-2020
dc.date.accessioned2024-07-03T12:57:12Z
dc.date.available2024-07-03T12:57:12Z
dc.date.issued2020-12-10
dc.description.abstractScrapie is a transmissible spongiform encephalopathy caused by prions and leads to neurodegeneration in the Central Nervous System (CNS) of sheep and goats. Genetic resistance/susceptibility to scrapie is well studied and it is known that the variations of 136th, 154th and 171st codons at the ovine PRNP gene have a major effect on the development of the disease. Many studies demonstrated that selection for PRNP genotypes has not influenced other performance traits, nevertheless, there is a knowledge gap about the possible link between the PRNP gene and the status of the other important diseases that affect the sheep population worldwide. In the present study, we tested whether there is an association between scrapie-related PRNP genotypes and fecal egg count (FEC) of gastrointestinal nematodes in seven adult Turkish sheep breeds. For this purpose, FEC scores of studied sheep (n = 253) were determined and the same animals were genotyped for the PRNP gene. Finally, an association analysis was performed for scrapie resistant (ARR), susceptible (VRQ), and wild-type (ARQ) haplotypes. Based on our statistical analysis, it is concluded that PRNP genotypes have no positive or negative effect on the FEC scores of adult sheep.
dc.description.sponsorshipT.C. Tarım ve Orman Bakanlığı Tarımsal Araştırmalar ve Politikalar Genel Müdürlüğü - TAGEM/HAYSUD/15/A01/P02/02-02
dc.identifier.doi10.1080/10495398.2020.1862136
dc.identifier.endpage387
dc.identifier.issn1049-5398
dc.identifier.issue3
dc.identifier.startpage381
dc.identifier.urihttps://doi.org/10.1080/10495398.2020.1862136
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/10495398.2020.1862136
dc.identifier.urihttps://hdl.handle.net/11452/42839
dc.identifier.volume32
dc.identifier.wos000601367100001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherTaylor & Francis
dc.relation.journalAnimal Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectProduction traits
dc.subjectProtein
dc.subjectPrp
dc.subjectAssociations
dc.subjectResistance
dc.subjectGenotypes
dc.subjectScrapie
dc.subjectGenetic resistance
dc.subjectPrnp gene
dc.subjectFecal egg count
dc.subjectTurkish native sheep
dc.subjectAgriculture
dc.subjectBiotechnology & applied microbiology
dc.titleDetecting fecal egg count (FEC) for gastrointestinal nematodes of adult Turkish sheep with different scrapie related PRNP haplotypes
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublicatione626aa13-7feb-4000-b304-87312f34b1d9
relation.isAuthorOfPublication03ea09a4-7777-4505-ae3a-6c03f66f7534
relation.isAuthorOfPublication2bd941dc-a19f-4cb7-abca-08f47bccee4c
relation.isAuthorOfPublication.latestForDiscoverye626aa13-7feb-4000-b304-87312f34b1d9

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