Publication:
Immune response of cattle to botulinum type C and D toxoid administered on three occasions

dc.contributor.authorMecitoğlu, Zafer
dc.contributor.authorTemizel, Ethem Mutlu
dc.contributor.authorÖzyigit, Özgür
dc.contributor.authorAkgül, Gülşah
dc.contributor.authorKennerman, Engin
dc.contributor.buuauthorMECİTOĞLU, ZAFER
dc.contributor.buuauthorTEMİZEL, ETHEM MUTLU
dc.contributor.buuauthorÖZYİĞİT, MUSA ÖZGÜR
dc.contributor.buuauthorAkgül, Gülşah
dc.contributor.buuauthorKENNERMAN, ENGİN
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Dahiliye Anabilim Dalı
dc.contributor.researcheridAAH-1677-2021
dc.contributor.researcheridECV-4083-2022
dc.contributor.researcheridGLP-3036-2022
dc.contributor.researcheridCBU-1718-2022
dc.contributor.researcheridFDU-5862-2022
dc.date.accessioned2024-07-31T12:50:20Z
dc.date.available2024-07-31T12:50:20Z
dc.date.issued2015-01-01
dc.description.abstractThe aims of the present study were to investigate the antibody response of cows from an outbreak region to vaccination with a bivalent botulinum toxoid (Type C and D) on three occasions and to investigate the antibody response to vaccination with the botulinum toxoid in the presence of anti-BoNT antibodies. Twenty-two cows from an outbreak region and 10 cows from a farm without a history of botulism were used in this study. Blood samples were collected before each vaccination and three weeks after the third vaccination (days 0, 21, 42 and 63). The level of anti-BoNT/C antibodies steadily increased after each vaccination (0.471 +/- 0.04, 0.566 +/- 0.03 and 0.663 +/- 0.04, respectively); however, the levels of anti-BoNT/ D antibodies were not significantly different after the second and third vaccinations (0.377 +/- 0.03, 0.493 +/- 0.03 and 0.465 +/- 0.03, respectively). Post vaccination antibody responses of animals found positive and negative for anti-BoNT antibodies at the beginning of the study were similar. The results of the present study indicated that vaccination of cattle with botulinum toxoid on three occasions is recommended, particularly in outbreaks that are suspected to be caused by BoNT/C and that presence of naturally acquired antibodies against BoNT did not interfere with post vaccination immune response.
dc.description.sponsorshipTürkiye Cumhuriyeti Kalkınma Bakanlığı
dc.identifier.eissn2074-7764
dc.identifier.endpage235
dc.identifier.issn0253-8318
dc.identifier.issue2
dc.identifier.startpage231
dc.identifier.urihttps://d1wqtxts1xzle7.cloudfront.net/93765329/231-235-libre.pdf
dc.identifier.urihttps://hdl.handle.net/11452/43587
dc.identifier.volume35
dc.identifier.wos000353175600021
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherUniv Agriculture, Fac Veterinary Science
dc.relation.journalPakistan Veterinary Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDairy-cattle
dc.subjectVaccination
dc.subjectHerd
dc.subjectImmunogenicity
dc.subjectDiagnosis
dc.subjectOutbreaks
dc.subjectVaccines
dc.subjectAntibody
dc.subjectBont
dc.subjectBotulism
dc.subjectElisa
dc.subjectVaccination
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectVeterinary sciences
dc.titleImmune response of cattle to botulinum type C and D toxoid administered on three occasions
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication66f17370-913f-4987-b8fb-1e44969deff2
relation.isAuthorOfPublication32cdabad-4bba-40b7-b2b6-b36bb228ea66
relation.isAuthorOfPublication3a2cbbbb-163d-428a-9caa-27708d631560
relation.isAuthorOfPublication2019f522-0190-4eae-ab7f-8ccc5f808697
relation.isAuthorOfPublication.latestForDiscovery66f17370-913f-4987-b8fb-1e44969deff2

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