Publication: Neutrophil lymphocyte ratio can be a valuable marker in defining disease activity in patients who have started antitumor necrosis factor (tnf) drugs for ankylosing spondylitis
dc.contributor.buuauthor | Coşkun, Belkis Nihan | |
dc.contributor.buuauthor | COŞKUN, BELKIS NİHAN | |
dc.contributor.buuauthor | Öksüz, Mustafa Ferhat | |
dc.contributor.buuauthor | Ermurat, Selime | |
dc.contributor.buuauthor | Tufan, Ayse Nur | |
dc.contributor.buuauthor | Oruçoğlu, Nurdan | |
dc.contributor.buuauthor | Doğan, Akif | |
dc.contributor.buuauthor | Dalkılıç, Ediz | |
dc.contributor.buuauthor | Pehlivan, Yavuz | |
dc.contributor.buuauthor | PEHLİVAN, YAVUZ | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı. | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı. | |
dc.contributor.orcid | 0000-0002-8613-5373 | |
dc.contributor.researcherid | AAG-7155-2021 | |
dc.contributor.researcherid | AAG-8227-2021 | |
dc.contributor.researcherid | ABE-4424-2022 | |
dc.contributor.researcherid | D-2589-2017 | |
dc.date.accessioned | 2024-09-11T12:49:35Z | |
dc.date.available | 2024-09-11T12:49:35Z | |
dc.date.issued | 2014-09-01 | |
dc.description.abstract | Objective: Neutrophil lymphocyte ratio (NLR) has emerged as a valuable and reliable method for follow-up of systemic inflammatory disease. We herein aimed to evaluate the role of NLR in the clinical follow-up of inflammation and also to compare its relationship with other measures, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).Material and Methods: A total of 35 active ankylosing spondylitis (AS) and 38 healthy volunteers were included in the study. The patient group was enrolled for treatment with one anti-tumor necrosis factor (TNF) drug. Total blood count, ESR, CRP, and BASDAI score were obtained before and 3 months following the treatment. NLR was found with a mathematical calculation of the ratio of neutrophils with lymphocytes.Results: The mean NLR value of the control group and patients was 1.90 +/- 0.89 and 2.67 +/- 1.17, respectively (p< 0.05). After a 3-month course of treatment, the patient group had a mean NLR value of 1.8 +/- 0.7, which was significantly lower than pretreatment values (p< 0.001). The posttreatment mean ESR, CRP, and BASDAI scores were significantly lower than mean baseline scores (p< 0.001, p= 0.007, p< 0.001, respectively). Also, NLR was found to be correlated with BASDAI, ESR, and CRP (r= 0.388, p< 0.001; r= 0.455, p< 0.0001; and r= 0.3389, p< 0.005, respectively).Conclusion: Neutrophil lymphocyte ratio could be a reliable and easily accessible method for follow-up of patients with AS. | |
dc.identifier.doi | 10.5152/eurjrheumatol.2014.034 | |
dc.identifier.endpage | 105 | |
dc.identifier.issn | 2147-9720 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 101 | |
dc.identifier.uri | https://doi.org/10.5152/eurjrheumatol.2014.034 | |
dc.identifier.uri | https://hdl.handle.net/11452/44588 | |
dc.identifier.volume | 1 | |
dc.identifier.wos | 000218664400004 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Aves | |
dc.relation.journal | European Journal Of Rheumatology | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Ankylosing spondylitis | |
dc.subject | Neutrophil lymphocyte ratio | |
dc.subject | Disease activity | |
dc.subject | Science & technology | |
dc.subject | Life sciences & biomedicine | |
dc.subject | Rheumatology | |
dc.title | Neutrophil lymphocyte ratio can be a valuable marker in defining disease activity in patients who have started antitumor necrosis factor (tnf) drugs for ankylosing spondylitis | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | faabfe30-a620-4cbe-8b6d-3db71b10ce0e | |
relation.isAuthorOfPublication | 1613225c-2f43-4052-9f82-210c854edcf4 | |
relation.isAuthorOfPublication | 0075f2ae-ae8a-4690-bd46-128775e8efac | |
relation.isAuthorOfPublication.latestForDiscovery | faabfe30-a620-4cbe-8b6d-3db71b10ce0e |
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