Publication:
Comparison of intraarticular bupivacaine and levobupivacaine with morphine and epinephrine for knee arthroscopy

dc.contributor.authorÖzdemir, Nurdan
dc.contributor.authorKaya, Fatma Nur
dc.contributor.authorGurbet, Alp
dc.contributor.authorYılmazlar, Aysun
dc.contributor.authorDemirağ, Burak
dc.contributor.authorMandıracı, Bilgen Onbaşı
dc.contributor.buuauthorÖzdemir, Nurdan
dc.contributor.buuauthorKAYA, FATMA NUR
dc.contributor.buuauthorGURBET, ALP
dc.contributor.buuauthorYılmazlar, Aysun
dc.contributor.buuauthorDemirağ, Burak
dc.contributor.buuauthorMandıracı, Bilgen Onbaşı
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Ortopedi Anabilim Dalı.
dc.contributor.orcid0000-0002-6503-8232
dc.contributor.researcheridDKY-7182-2022
dc.contributor.researcheridHPG-2667-2023
dc.contributor.researcheridA-7994-2018
dc.contributor.researcheridGKF-2266-2022
dc.contributor.researcheridEVT-6166-2022
dc.contributor.researcheridFIF-3175-2022
dc.date.accessioned2024-10-04T12:17:22Z
dc.date.available2024-10-04T12:17:22Z
dc.date.issued2013-06-01
dc.description.abstractObjective: To compare the efficacy of intraarticularly injected bupivacaine with levobupivacaine when administered in combination with morphine and adrenaline for post-operative analgesia and functional recovery after knee surgery.Materials and Methods: Sixty American Society of Anesthesiologists physical status I-II patients were randomized into three groups: Group B was administered 30 mL isobaric 0.5% bupivacaine, 2 mg morphine and 100 mu g adrenaline, Group L was administered 30 mL 0.5% levobupivacaine, 2 mg morphine and 100 mu g adrenaline, and Group C was administered 30 mL 0.9% NaCl solution into the knee joint by the surgeon at the end of surgery. The morphine usage and visual analog pain scores were recorded regularly afterwards. We also recorded the time that elapsed before each patients' first mobilization, positive response to straight leg raising, tolerance to 30-50 degrees knee flexion, recovery of quadriceps reflexes and discharge from the hospital. We also recorded patient and surgeon satisfaction.Results: The pain scale values were lower in Groups B and L than in Group C at 2, 4, 6, 8, 12 and 24 hours post-operatively (all p<0.001). In Groups B and L, the time for first analgesic request was longer (p<0.01), the morphine consumption was lower (p<0.001), and the duration of morphine usage was shorter (p<0.001). The times to positive response to straight leg raising, tolerance to 30-50 degrees knee flexion and the first mobilization were shorter in Groups B and L (p<0.001 for all).Conclusion: After arthroscopic knee surgery, intraarticular levobupivacaine combined with morphine and adrenaline decreases analgesic requirements, shortens the postoperative duration of analgesic use and hastens mobilization as effectively as bupivacaine.
dc.identifier.doi10.5152/eajm.2013.18
dc.identifier.endpage82
dc.identifier.issn1308-8734
dc.identifier.issue2
dc.identifier.startpage77
dc.identifier.urihttps://doi.org/10.5152/eajm.2013.18
dc.identifier.urihttps://www.eajm.org//en/comparison-of-intraarticular-bupivacaine-and-levobupivacaine-with-morphine-and-epinephrine-for-knee-arthroscopy-132629
dc.identifier.urihttps://hdl.handle.net/11452/45895
dc.identifier.volume45
dc.identifier.wos000420432000002
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherAves
dc.relation.journalEurasian Journal of Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectArthroscopic surgery
dc.subjectBupivacaine
dc.subjectIntraarticular injection
dc.subjectLevobupivacaine
dc.subjectPostoperative pain
dc.subjectGeneral & internal medicine
dc.titleComparison of intraarticular bupivacaine and levobupivacaine with morphine and epinephrine for knee arthroscopy
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication9e72832d-356c-409c-a2b1-16a2bfe825c3
relation.isAuthorOfPublicationfc04310c-770b-4b0f-89a3-3ed0ffafbc66
relation.isAuthorOfPublication.latestForDiscovery9e72832d-356c-409c-a2b1-16a2bfe825c3

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