Publication:
Phenotypic characterization and differentiation of mesenchymal stem cells originating from adipose tissue

dc.contributor.authorÇerçi, Ece
dc.contributor.authorErdost, Hatice
dc.contributor.buuauthorÇerçi, Ece
dc.contributor.buuauthorERDOST, HATİCE
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/Histoloji ve Embriyoloji Anabilim Dalı.
dc.contributor.orcid0000-0002-2740-4262
dc.contributor.researcheridAAH-9216-2021
dc.contributor.researcheridFYC-9982-2022
dc.date.accessioned2024-10-23T06:06:52Z
dc.date.available2024-10-23T06:06:52Z
dc.date.issued2019-01-01
dc.description.abstractStem cells are known as undifferentiated cells that are capable of divisions and self-renewal over an extended period. Adipose tissue-derived mesenchymal stem cells (ADSCs) are known to differentiate into many different organ and tissue cells. The purpose of this study was to characterize adipose tissue-derived mesenchymal stem cells in detail based on the expression status of certain surface markers and differentiation stages for clinical and laboratory applications. The migrating phase and mitotic property of the cells from adipose tissue were assessed under a microscope. Cell counting was performed during the first, second, and third passages. The cells were differentiated into osteogenic, chondrogenic, and adipogenic lineages. Stem cells were characterized by immunostaining of CD90, CD105, CD11b, and CD45 surface markers. ADSC growth kinetics were determined at the first, second, and third passages. In conclusion, ADSCs were reported in detail here based on surface markers and differentiation potentials, growth curves, and population doubling times during the first, second, and third passages.
dc.identifier.doi10.3906/vet-1810-61
dc.identifier.endpage845
dc.identifier.issn1300-0128
dc.identifier.issue6
dc.identifier.startpage834
dc.identifier.urihttps://doi.org/10.3906/vet-1810-61
dc.identifier.urihttps://journals.tubitak.gov.tr/veterinary/vol43/iss6/16/
dc.identifier.urihttps://hdl.handle.net/11452/46892
dc.identifier.volume43
dc.identifier.wos000500746600016
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherTÜBİTAK
dc.relation.bapOUAP 2015/25
dc.relation.journalTurkish Journal of Veterinary & Animal Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectStromal cells
dc.subjectExpression
dc.subjectAdscs
dc.subjectDifferentiation
dc.subjectCharacterization
dc.subjectGrowth curve
dc.subjectPopulation doubling time
dc.subjectVeterinary sciences
dc.titlePhenotypic characterization and differentiation of mesenchymal stem cells originating from adipose tissue
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication0442e63c-5492-4be6-a278-c4413a82210f
relation.isAuthorOfPublication.latestForDiscovery0442e63c-5492-4be6-a278-c4413a82210f

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