Publication:
Open-label trial of cyclosporine for vulvar lichen sclerosus

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dc.contributor.buuauthorBaşkan, Emel Bülbül
dc.contributor.buuauthorTuran, Hakan
dc.contributor.buuauthorTunalı, Şükran
dc.contributor.buuauthorToker, Semra Çıkman
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentDermatoloji Anabiilim Dalı
dc.contributor.orcid0000-0002-0144-3263
dc.contributor.researcheridAAH-1388-2021
dc.contributor.scopusid6602518817
dc.contributor.scopusid16835681500
dc.contributor.scopusid7004191748
dc.contributor.scopusid14054750900
dc.contributor.scopusid6603722836
dc.date.accessioned2022-10-24T08:59:59Z
dc.date.available2022-10-24T08:59:59Z
dc.date.issued2007-08
dc.description.abstractBackground: Lichen sclerosus (LS) is a chronic inflammatory disease of skin and mucosal surfaces which is generally difficult to treat. Objective: We evaluated the efficacy of oral cyclosporine in refractory vulvar LS. Methods: Five patients with refractory vulvar LS were treated with oral cyclosporine (3-4 mg/kg/d) for 3 months. They were followed up on a monthly basis. Results: At the end of the treatment, the mean total symptom score regressed significantly and clinical findings such as erythema and erosion showed marked improvement. Mild adverse effects were seen in 3 patients. Limitations: The patients did not give consent to rebiopsy at the end of the treatment. Conclusion: Moderate dose of oral cyclosporine could be an effective alternative in the treatment of refractory vulvar LS.
dc.identifier.citationBaşkan, E. B. vd. (2007). "Open-label trial of cyclosporine for vulvar lichen sclerosus". Journal of the American Academy of Dermatology, 57(2), 276-278.
dc.identifier.endpage278
dc.identifier.issn0190-9622
dc.identifier.issue2
dc.identifier.pubmed17442452
dc.identifier.scopus2-s2.0-34447257389
dc.identifier.startpage276
dc.identifier.urihttps://doi.org/10.1016/j.jaad.2007.03.006
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0190962207005403
dc.identifier.urihttp://hdl.handle.net/11452/29191
dc.identifier.volume57
dc.identifier.wos000248340000011
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherMosby Elsevier
dc.relation.journalJournal of the American Academy of Dermatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDermatology
dc.subjectClobetasol
dc.subject.emtreePimecrolimus
dc.subject.emtreeCalcipotriol
dc.subject.emtreeClobetasol
dc.subject.emtreeCyclosporin
dc.subject.emtreeEstrogen
dc.subject.emtreeTestosterone
dc.subject.emtreePriority journal
dc.subject.emtreeLichen sclerosus et atrophicus
dc.subject.emtreeAdult
dc.subject.emtreeAged
dc.subject.emtreeArticle
dc.subject.emtreeClinical article
dc.subject.emtreeDrug dose reduction
dc.subject.emtreeDrug efficacy
dc.subject.emtreeErosion
dc.subject.emtreeErythema
dc.subject.emtreeFemale
dc.subject.emtreeFollow up
dc.subject.emtreeHuman
dc.subject.emtreeRemission
dc.subject.emtreeOutcome assessment
dc.subject.emtreeOpen study
dc.subject.emtreeRetrospective study
dc.subject.emtreeTreatment duration
dc.subject.emtreeTreatment response
dc.subject.meshAdministration, oral
dc.subject.meshFollow-up studies
dc.subject.meshAdministration, topical
dc.subject.meshAged
dc.subject.meshAnti-inflammatory agents
dc.subject.meshClobetasol
dc.subject.meshCyclosporine
dc.subject.meshFemale
dc.subject.meshVulvar lichen sclerosus
dc.subject.meshHumans
dc.subject.meshMiddle aged
dc.subject.meshOintments
dc.subject.meshRetrospective studies
dc.subject.meshTreatment outcome
dc.subject.scopusLichen Sclerosus Et Atrophicus; Vulva Kraurosis; Balanitis Xerotica Obliterans
dc.subject.wosDermatology
dc.titleOpen-label trial of cyclosporine for vulvar lichen sclerosus
dc.typeArticle
dc.wos.quartileQ1
dc.wos.quartileQ1
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Dermatoloji Anabiilim Dalı
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus

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