Publication:
Flow cytometric analysis of T, B, and NK cells antigens in patients with mycosis fungoides

dc.contributor.authorYazıcı, Serkan
dc.contributor.authorBaşkan, Emel Bülbül
dc.contributor.authorBudak, Ferah
dc.contributor.authorOral, Barbaros
dc.contributor.authorAdım, Şaduman Balaban
dc.contributor.authorKalın, Zübeyde Ceylan
dc.contributor.authorÖzkaya, Güven
dc.contributor.authorAydoğan, Kenan
dc.contributor.authorSarıcaoğlu, Hayriye
dc.contributor.authorTunalı, Şükran
dc.contributor.buuauthorYAZİCİ, SERKAN
dc.contributor.buuauthorBÜLBÜL BAŞKAN, EMEL
dc.contributor.buuauthorBUDAK, FERAH
dc.contributor.buuauthorORAL, HALUK BARBAROS
dc.contributor.buuauthorBALABAN ADIM, ŞADUMAN
dc.contributor.buuauthorKalın, Zübeyde Ceylan
dc.contributor.buuauthorÖZKAYA, GÜVEN
dc.contributor.buuauthorAYDOĞAN, KENAN
dc.contributor.buuauthorSARICAOĞLU, HAYRİYE
dc.contributor.buuauthorTunalı, Şükran
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentDermatoloji ve Zührevi Hastalıklar Ana Bilim Dalı
dc.contributor.orcid0000-0001-6407-0962
dc.contributor.orcid0000-0001-7625-9148
dc.contributor.orcid0000-0003-0463-6818
dc.contributor.orcid0000-0003-0297-846X
dc.contributor.orcid0000-0002-0193-1128
dc.contributor.researcheridIZP-9398-2023
dc.contributor.researcheridAAH-2459-2021
dc.contributor.researcheridAAH-1388-2021
dc.contributor.researcheridA-4421-2016
dc.contributor.researcheridF-4657-2014
dc.contributor.researcheridAAH-6216-2021
dc.contributor.researcheridK-7285-2012
dc.contributor.researcheridEMN-0789-2022
dc.contributor.researcheridCWV-8710-2022
dc.contributor.researcheridDPU-8534-2022
dc.contributor.researcheridGGH-7385-2022
dc.date.accessioned2024-08-08T08:51:40Z
dc.date.available2024-08-08T08:51:40Z
dc.date.issued2015-11-24
dc.description.abstractWe retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral blood flow cytometry as part of their first visit. TNMB and histopathological staging of the cases were retrospectively performed in accordance with International Society forCutaneous Lymphomas/European Organization of Research and Treatment of Cancer (ISCL/EORTC) criteria at the time of flow cytometry sampling. To determine prognostic value of cell surface antigens, cases were divided into two groups as stable and progressive disease. 17 flow cytometric analyses of 17 parapsoriasis (PP) and 11 analyses of 11 benign erythrodermic patients were included as control groups. Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3(+), CD4(+), CD8(+), TCR alpha beta(+), TCR gamma delta(+), CD7(+), CD4(+) CD7(+), CD4(+) CD7(-), and CD71(+)), B cells (HLA-DR+, CD19(+), and HLA-DR(+)CD19(+)), NKT cells (CD3(+)CD16(+)CD56(+)), and NK cells (CD3(-)CD16(+)CD56(+)). The mean value of all cell surface antigens was not statistically significant between parapsoriasis and MF groups. Along with an increase in cases of MF stage statistically significant difference was found between the mean values of cell surface antigens. Flow cytometric analysis of peripheral blood cell surface antigens in patients with mycosis fungoides may contribute to predicting disease stage and progression.
dc.identifier.doi10.1155/2015/856340
dc.identifier.issn2314-8861
dc.identifier.urihttps://doi.org/10.1155/2015/856340
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1155/2015/856340
dc.identifier.urihttps://hdl.handle.net/11452/43807
dc.identifier.volume2015
dc.identifier.wos000367304300001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherHindawi
dc.relation.journalJournal of Immunology Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLymphoma task-force
dc.subjectSezary-syndrome
dc.subjectInternational-society
dc.subjectEuropean-organization
dc.subjectCutaneous-lymphomas
dc.subjectBlood involvement
dc.subjectDiagnosis
dc.subjectCd4+
dc.subjectImmunology
dc.titleFlow cytometric analysis of T, B, and NK cells antigens in patients with mycosis fungoides
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Dermatoloji ve Zührevi Hastalıklar Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/İmmünoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Patoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Biyoistatistik Ana Bilim Dalı
relation.isAuthorOfPublication9bc5c730-985b-47f5-a6ce-72d472c96078
relation.isAuthorOfPublication5bd3accb-bb59-411b-8d6c-46d06d35b5a4
relation.isAuthorOfPublication26fb3aa9-55a8-4fa3-8a4a-9c449958d4f5
relation.isAuthorOfPublicationbc853dab-a811-42b9-b03b-6d5fe067efe8
relation.isAuthorOfPublication80df1863-762d-4cc1-9313-2d77d9e79ff8
relation.isAuthorOfPublication648e85b9-2f4f-4f92-a2d7-794286abd0fd
relation.isAuthorOfPublication25c8c1ea-a743-4c4b-b62f-8b4f6a11ef75
relation.isAuthorOfPublication3a2758ac-215f-4821-ac4e-c5c751cd298b
relation.isAuthorOfPublication.latestForDiscovery9bc5c730-985b-47f5-a6ce-72d472c96078

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Yazici_vd_2015.pdf
Size:
518.21 KB
Format:
Adobe Portable Document Format

Collections