Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators

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dc.contributor.authorBridoux, Alexandre
dc.contributor.authorCui, Huadong
dc.contributor.authorDyskin, Evgeny A.
dc.contributor.authorMousa, Shaker A.
dc.contributor.buuauthorYalçın, Murat
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Fizyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-5600-8162tr_TR
dc.contributor.researcheridAAG-6956-2021tr_TR
dc.contributor.scopusid57192959734tr_TR
dc.date.accessioned2021-12-10T08:12:08Z
dc.date.available2021-12-10T08:12:08Z
dc.date.issued2009-06-15
dc.description.abstractNovel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity.en_US
dc.identifier.citationBridoux, A. vd. (2009). "Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators". Bioorganic and Medicinal Chemistry Letters, 19(12), 3259-3263.en_US
dc.identifier.endpage3263tr_TR
dc.identifier.issn0960-894X
dc.identifier.issue12tr_TR
dc.identifier.pubmed19427201tr_TR
dc.identifier.scopus2-s2.0-65749099626tr_TR
dc.identifier.startpage3259tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.bmcl.2009.04.094
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0960894X09006040
dc.identifier.urihttp://hdl.handle.net/11452/23162
dc.identifier.volume19tr_TR
dc.identifier.wos000266402000024tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.relation.collaborationYurt dışıtr_TR
dc.relation.journalBioorganic and Medicinal Chemistry Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiogenesisen_US
dc.subjectEsterificationen_US
dc.subjectHPLCen_US
dc.subjectNanopharmaceutical technologyen_US
dc.subjectSilylationen_US
dc.subjectTetracen_US
dc.subjectIntegrin alpha-v-beta-3en_US
dc.subjectExtracellular segmenten_US
dc.subjectCrystal-structureen_US
dc.subjectTriiodothyronineen_US
dc.subjectThyroxineen_US
dc.subjectLiganden_US
dc.subjectAciden_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectChemistryen_US
dc.subject.emtreeAngiogenesis inhibitoren_US
dc.subject.emtreeFibroblast growth factoren_US
dc.subject.emtreeIodine derivativeen_US
dc.subject.emtreePhenol derivativeen_US
dc.subject.emtreeAngiogenesisen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeAntiangiogenic activityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChick embryoen_US
dc.subject.emtreeChorioallantoisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeDrug potencyen_US
dc.subject.emtreeDrug synthesisen_US
dc.subject.emtreeEmbryoen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMouseen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreeStructure activity relationen_US
dc.subject.meshAngiogenesis inhibitorsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChick embryoen_US
dc.subject.meshChorioallantoic membraneen_US
dc.subject.meshDrug evaluation, preclinicalen_US
dc.subject.meshFibroblast growth factorsen_US
dc.subject.meshHemoglobinsen_US
dc.subject.meshMiceen_US
dc.subject.meshStructure-activity relationshipen_US
dc.subject.meshThyroxineen_US
dc.subject.scopusTetraiodothyroacetic Acid; Thyroid Hormones; Nano-Diamino-Tetracen_US
dc.subject.wosChemistry, medicinalen_US
dc.subject.wosChemistry, organicen_US
dc.titleSemisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulatorsen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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