Effect of chitosan coating on surgical sutures to strengthen the colonic anastomosis
dc.contributor.author | Chung, Soon Soup | |
dc.contributor.buuauthor | Altınel, Yüksel | |
dc.contributor.buuauthor | Okay, Güven | |
dc.contributor.buuauthor | Uğraş, Nesrin | |
dc.contributor.buuauthor | Işık, Ahmet Fatih | |
dc.contributor.buuauthor | Öztürk, Ersin | |
dc.contributor.buuauthor | Özgüç, Halil | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Genel Cerrahi Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Kliniği. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tekstil Mühendisliği Fakültesi/Tekstil Bölümü. | tr_TR |
dc.contributor.researcherid | AAL-9231-2020 | tr_TR |
dc.contributor.researcherid | AAH-2716-2021 | tr_TR |
dc.contributor.scopusid | 26657125600 | tr_TR |
dc.contributor.scopusid | 57204588493 | tr_TR |
dc.contributor.scopusid | 55386535600 | tr_TR |
dc.contributor.scopusid | 56217319800 | tr_TR |
dc.contributor.scopusid | 35070171400 | tr_TR |
dc.contributor.scopusid | 6603867989 | tr_TR |
dc.date.accessioned | 2024-01-15T05:56:56Z | |
dc.date.available | 2024-01-15T05:56:56Z | |
dc.date.issued | 2018-09 | |
dc.description.abstract | BACKGROUND: We evaluated the feasibility of chitosan-coated sutures for intestinal anastomosis strength through wound-healing effect. METHODS: Vicryl and PDS sutures were coated with 2% chitosan. While laparotomy was applied to the first group, chitosan was applied in the peritoneal cavity in the second group. Then the following materials were applied to colon anastomosis, in order: Vicryl, PDS, chitosan-coated Vicryl, and chitosan-coated PDS sutures. On the 7th and 14th days, eight rats from each group were euthanized. RESULTS: The adhesion scores of chitosan and control groups were lower than the suture groups. The vascularization of Vicryl-chitosan was lower than PDS-chitosan on the 14th day (p=0.038). Fibroblast cells and vascularization of anastomosis with chitosan-coated Vicryl were lower than Vicryl and chitosan-coated PDS on the 14th day (p<0.05). The tensile strength of Vicryl-chitosan increased more than Vicryl in vitro (p<0.05) on the 14th and 7th days, but there was no difference in vivo. The tensile strength of PDS-chitosan decreased more than PDS on the 7th day in vivo (p<0.05). CONCLUSION: The chitosan-coating effect on the adhesion and reinforcement of anastomosis in some parts of Vicryl in vitro and PDS in vivo was slightly improved. | en_US |
dc.identifier.citation | Altınel, Y. vd. (2018). ''Effect of chitosan coating on surgical sutures to strengthen the colonic anastomosis''. Ulusal Travma ve Acil Cerrahi Dergisi, 24(5), 405-411. | en_US |
dc.identifier.doi | https://doi.org/10.5505/tjtes.2018.59280 | en_US |
dc.identifier.endpage | 411 | tr_TR |
dc.identifier.issn | 1306-696X | |
dc.identifier.issue | 5 | tr_TR |
dc.identifier.pubmed | 30394492 | tr_TR |
dc.identifier.scopus | 2-s2.0-85056273699 | tr_TR |
dc.identifier.startpage | 405 | tr_TR |
dc.identifier.uri | https://jag.journalagent.com/travma/pdfs/UTD-59280-RESEARCH_ARTICLE-ALTINEL.pdf | en_US |
dc.identifier.uri | https://hdl.handle.net/11452/39004 | |
dc.identifier.volume | 24 | tr_TR |
dc.identifier.wos | 000446506600005 | |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Türk Travma ve Acil Cerrahi Derneği | tr_TR |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.relation.journal | Ulusal Travma ve Acil Cerrahi Dergisi | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Emergency medicine | en_US |
dc.subject | Anastomosis | en_US |
dc.subject | Chitosan | en_US |
dc.subject | PDS suture | en_US |
dc.subject | Tensile strength | en_US |
dc.subject | Vicryl suture | en_US |
dc.subject | Wound healing | en_US |
dc.subject | In-vitro | en_US |
dc.subject | Postsurgical adhesions | en_US |
dc.subject | Peritoneal adhesion | en_US |
dc.subject | Repair | en_US |
dc.subject | Reduction | en_US |
dc.subject | Tensile | en_US |
dc.subject.emtree | Chitosan | en_US |
dc.subject.emtree | Collagen | en_US |
dc.subject.emtree | Biocompatible coated material | en_US |
dc.subject.emtree | Angiogenesis | en_US |
dc.subject.emtree | Animal experiment | en_US |
dc.subject.emtree | Animal tissue | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Cell infiltration | en_US |
dc.subject.emtree | Colon anastomosis | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Device safety | en_US |
dc.subject.emtree | Evaluation study | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Fibroblast | en_US |
dc.subject.emtree | Histopathology | en_US |
dc.subject.emtree | Inflammatory cell | en_US |
dc.subject.emtree | Intestine surgery | en_US |
dc.subject.emtree | Laparotomy | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Rat | en_US |
dc.subject.emtree | Risk assessment | en_US |
dc.subject.emtree | Scoring system | en_US |
dc.subject.emtree | Suture technique | en_US |
dc.subject.emtree | Tensile strength | en_US |
dc.subject.emtree | Tissue adhesion | en_US |
dc.subject.emtree | Wound healing | en_US |
dc.subject.emtree | Anastomosis | en_US |
dc.subject.emtree | Animal | en_US |
dc.subject.emtree | Colon | en_US |
dc.subject.emtree | Drug effect | en_US |
dc.subject.emtree | Procedures | en_US |
dc.subject.emtree | Surgery | en_US |
dc.subject.emtree | Suture | en_US |
dc.subject.emtree | Tissue adhesion | en_US |
dc.subject.emtree | Wound healing | en_US |
dc.subject.mesh | Anastomosis, surgical | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Chitosan | en_US |
dc.subject.mesh | Coated materials, biocompatible | en_US |
dc.subject.mesh | Colon | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Sutures | en_US |
dc.subject.mesh | Tissue adhesions | en_US |
dc.subject.mesh | Wound healing | en_US |
dc.subject.scopus | Sutures; Triclosan; Surgical Infection | en_US |
dc.subject.wos | Emergency medicine | en_US |
dc.title | Effect of chitosan coating on surgical sutures to strengthen the colonic anastomosis | en_US |
dc.type | Article | en_US |
dc.wos.quartile | Q4 (Emergency medicine) | en_US |