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Recent Submissions

Publication
Numerical simulation and analytical evaluation of the collection efficiency of the particles in a gas by the wire-plate electrostatic precipitators
(MDPI, 2022-07-01) Kılıç, Muhsin; Mutlu, Mustafa; Altun, Ayşe Fidan; KILIÇ, MUHSİN; MUTLU, MUSTAFA; ALTUN, AYŞE FİDAN; Bursa Uludağ Üniversitesi/Mühendislik Fakültesi/Makine Mühendisliği Bölümü; Bursa Uludağ Üniversitesi/Yenişehir İbrahim Orhan Meslek Yüksekokulu; Bursa Uludağ Üniversitesi/Orhangazi Yeniköy Asil Çelik Meslek Yüksekokulu; 0000-0003-2113-4510; 0000-0001-7236-8398; 0000-0001-6816-8377; O-2253-2015; ABB-9566-2020; AAA-2005-2022
In this study, a numerical simulation model and an analytical method are introduced to evaluate the particle collection efficiency and transport phenomena in an electrostatic precipitator (ESP). Several complicated physical processes are involved in an ESP, including the turbulent flow, the ionization of gas by corona discharge, particles' movement, and the displacement of electric charge. The attachment of ions charges suspended particles in the gas media. Then, charged particles in the fluid move towards the collection plate and stick on it. The numerical model comprises the gas flow, electrostatic field, and particle motions. The collection efficiency of the wire-plate type ESP is investigated for the particle diameter range of 0.02 to 10 mu m. It is observed that electric field strengths and current densities show considerable variation in the solution domain. Meanwhile, changing supply voltage and charging wire diameters significantly affect the acquired charges on the electrostatic field and particle collecting efficiencies. Simultaneously, the distance between the charging and collecting electrodes and the main fluid inlet velocity has an important effect on the particle collection efficiency. The influence of the different ESP working conditions and particle dimensions on the performance of ESP are investigated and discussed.
Publication
Investigation of the influence of high-pressure torsion and solution treatment on corrosion and tribocorrosion behavior of CoCrMo alloys for biomedical applications
(Mdpi, 2023-04-01) Yılmazer, Hakan; Caha, İhsan; Dikici, Burak; Toptan, Fatih; Işık, Murat; Niinomi, Mitsuo; Nakai, Masaaki; Alves, Alexandra Cruz; IŞIK, MURAT; Bursa Uludağ Üniversitesi/Mühendislik Fakültesi/Otomotiv Mühendisliği Bölümü.; 0000-0002-6116-1882 ; GQP-1784-2022
In this study, the influence of the high-pressure torsion (HPT) processing parameters and solution treatment (ST) on the corrosion and tribocorrosion behavior of CoCrMo (CCM) alloys was investigated for possible usage in biomedical applications. The corrosion behavior of the CCM alloys was investigated by using potentiodynamic scanning (PDS) and electrochemical impedance spectroscopy (EIS) tests. Tribocorrosion tests were carried out in a reciprocating ball-on-plate tribometer at 1 Hz, 1 N load, and 3 mm stroke length for 2 h. All electrochemical measurements were performed using a potentiostat in standard phosphate-buffered saline (PBS) solution at body temperature (37 +/- 2 degrees C). The samples were characterized by using a scanning electron microscope (SEM), transmission electron microscope (TEM), optical microscope (OM), and X-ray diffraction (XRD). The deepness and width of wear tracks were examined by using a profilometer. The results showed that HPT and ST processes did not affect significantly the corrosion resistance of samples. However, the ST-treated samples had a higher material loss during sliding in standard phosphate-buffered saline (PBS) at body temperature as compared to HPT-treated samples.
Publication
Psychology of religion in the divinity school magazine related articles published in Turkey
(İlahiyat Bilimleri Araştırma Vakfi, 2005-01-01) Koç, Mustafa; Koç, Mustafa; Uludağ Üniversitesi/Sosyal Bilimler Enstitüsü/Din Psikolojisi; 0000-0002-9638-0196; JRQ-2279-2023
Publication
Investigation of the dual role of scorzonera pygmaea: Cytotoxic activity and antioxidant potential
(Wiley, 2023-10-19) Sarımahmut, Mehmet; SARIMAHMUT, MEHMET; Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü; 0000-0003-2647-5875; JCN-7113-2023
Scorzonera pygmaea, an indigenous plant of western Anatolia, belongs to the Scorzonera genus, which includes various species recognized for their edible and medicinal properties. This study is aimed at investigating the phenolic composition of S. pygmaea; evaluating its antioxidant, cytotoxic, apoptotic, and genotoxic activities; and assessing the impact of S. pygmaea on the expression of cell cycle regulatory genes. HPLC-DAD analysis identified chlorogenic acid as the predominant phenolic compound, potentially linking plant to dietary benefits. The antioxidant potential, evaluated using DPPH radical scavenging and CUPRAC assays, yielded an IC50 value of 63 53 +/- 6 29 pig/ml and a Trolox equivalent of 0 061 +/- 0 013 g/g, respectively. To assess antigrowth activity, the S. pygmaea extract was tested against MCF-7 and MDA-MB-231 breast cancer cell lines, along with the nonmalignant MCF-10A cell line, using sulforhodamine B and ATP cell viability assays. The results exhibited highly consistent IC50 values of 104.63, 179.27, and 90.83 pig/ml, respectively. Notably, the S. pygmaea extract induced apoptosis in all cell lines, with MDA-MB-231 cells displaying a higher percentage of early apoptotic cells under fluorescence microscopy. The comet assay revealed that S. pygmaea extract induced DNA damage in all cell lines, with MCF-7 and MCF-10A cells showing an accumulation of DNA damage over time. Gene expression analysis revealed significant alterations in cell cycle regulators, with each cell line displaying distinct and time-dependent patterns after exposure to S. pygmaea. Collectively, these findings underscore the cytotoxic, apoptotic, and genotoxic activities of S. pygmaea while simultaneously emphasizing its antioxidant potential, especially given its high chlorogenic acid content. The dual role of S. pygmaea, evidenced by its cytotoxic and antioxidant properties, suggests the potential for further exploration of its utilization within the food industry as a possible dietary resource, while necessitating further studies to fully understand its implications.
Publication
Towards homogenization of total body irradiation practices in pediatric patients across SIOPE affiliated centers. A survey by the SIOPE radiation oncology working group
(Elsevier Ireland Ltd, 2021-02-01) Hoeben, Bianca A. W.; Pazos, Montserrat; Albert, Michael H.; Seravalli, Enrica; Bosman, Mirjam E.; Losert, Christoph; Boterberg, Tom; Manapov, Farkhad; Ospovat, Inna; Milla, Soraya Mico; Abakay, Candan Demiröz; Engellau, Jacob; Kos, Gregor; Supiot, Stephane; Bierings, Marc; Janssens, Geert O.; DEMİRÖZ ABAKAY, CANDAN; Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; 0000-0001-5380-5898 ; AAH-3855-2021
Background and purpose: To reduce relapse risk, Total Body Irradiation (TBI) is part of conditioning regimens for hematopoietic stem cell transplantation (HSCT) in pediatric acute leukemia. The study purpose was to evaluate clinical practices regarding TBI, such as fractionation, organ shielding and delivery techniques, among SIOPE affiliated radiotherapy centers.Methods: An electronic survey was sent out to 233 SIOPE affiliated centers, containing 57 questions about clinical practice of TBI. Surveys could be answered anonymously.Results: From over 25 countries, 82 responses were collected. For TBI-performing centers, 40/48 irradiated <= 10 pediatric patients annually (range: 1-2 to >25). Most indications concerned acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML). Four different fractionation schedules were used, of which 12 Gy in 6 fractions was applied in 91% for ALL and 86% for AML. Dose reduction to the lungs, mostly to a mean dose of 8-10 Gy, was applied by 28/33 centers for ALL and 19/21 centers for AML, in contrast to much less applied dose reduction to the kidneys (7/33 ALL and 7/21 AML), thyroid (2/33 ALL and 2/21 AML), liver (4/33 ALL and 3/21 AML) and lenses (4/33 ALL and 4/21 AML). Conventional TBI techniques were used by 24/29 responding centers, while 5/29 used advanced optimized planning techniques.Conclusion: Across SIOPE, there is a high level of uniformity in fractionation and use of lung shielding. Practices vary regarding other organs-at-risk shielding and implementation of advanced techniques. A SIOPE radiotherapy working group will be established to define international guidelines for pediatric TBI. (C) 2020 The Author(s). Published by Elsevier B.V.
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