Publication: Carbapenem-resistant Gram-negative pathogens associated with septic shock: A review of 120 cases
dc.contributor.author | Önal, Uğur | |
dc.contributor.author | Akyol, Deniz | |
dc.contributor.author | Mert, Merve | |
dc.contributor.author | Baskol, Dilsah | |
dc.contributor.author | Memetali, Seichan Chousein | |
dc.contributor.author | Sanlidag, Gamze | |
dc.contributor.author | Kenanoglu, Buse | |
dc.contributor.author | Uyan-Onal, Ayse | |
dc.contributor.author | Quliyeva, Gunel | |
dc.contributor.author | Avsar, Cansu Bulut | |
dc.contributor.author | Akdag, Damla | |
dc.contributor.author | Demir, Melike | |
dc.contributor.author | Erdem, Huseyin Aytac | |
dc.contributor.author | Kahraman, Umit | |
dc.contributor.author | Bozbiyik, Osman | |
dc.contributor.author | Ozgiray, Erkin | |
dc.contributor.author | Bozkurt, Devrim | |
dc.contributor.author | Akarca, Funda Karbek | |
dc.contributor.author | Demirag, Kubilay | |
dc.contributor.author | Cankayali, Ilkin | |
dc.contributor.author | Uyar, Mehmet | |
dc.contributor.author | Cilli, Feriha | |
dc.contributor.author | Arda, Bilgin | |
dc.contributor.author | Yamazhan, Tansu | |
dc.contributor.author | Pullukcu, Husnu | |
dc.contributor.author | Tasbakan, Meltem Isikgoz | |
dc.contributor.author | Sipahi, Hilal | |
dc.contributor.author | Ulusoy, Sercan | |
dc.contributor.author | Sipahi, Oguz Resat | |
dc.contributor.buuauthor | ÖNAL, UĞUR | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, | |
dc.contributor.orcid | 0000-0001-6953-8499 | |
dc.contributor.researcherid | ACQ-7832-2022 | |
dc.date.accessioned | 2024-10-21T06:42:22Z | |
dc.date.available | 2024-10-21T06:42:22Z | |
dc.date.issued | 2022-04-16 | |
dc.description.abstract | This study aimed to evaluate the influencing variables for outcomes in patients with septic shock having culture-proven carbapenem-resistant Gram-negative pathogens. It included 120 patients (mean age 64.29 +/- 1.35 years and 58.3% female). The mean Sequential Organ Failure Assessment score during septic shock diagnosis was found to be 11.22 +/- 0.43 and 9 +/- 0.79 among the patients with mortality and among the survivors, respectively (P = 0.017). The logistic regression analysis showed that empirical treatment as mono Gram-negative bacteria-oriented antibiotic therapy (P = 0.016, odds ratio (OR) = 17.730, 95% confidence interval (CI): 1.728-182.691), Charlson Comorbidity Index >2 (P = 0.032, OR = 7.312, 95% CI: 5.7-18.3), and systemic inflammatory response syndrome score 3 or 4 during septic shock diagnosis (P = 0.014, OR = 5.675, 95% CI: 1.424-22.619) were found as independent risk factors for day 30 mortality. Despite early diagnosis and effective management of patients with septic shock, the mortality rates are quite high in CRGNP-infected patients. | |
dc.identifier.doi | 10.1080/1120009X.2022.2064703 | |
dc.identifier.endpage | 445 | |
dc.identifier.issn | 1120-009X | |
dc.identifier.issue | 7 | |
dc.identifier.startpage | 436 | |
dc.identifier.uri | https://doi.org/10.1080/1120009X.2022.2064703 | |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1080/1120009X.2022.2064703 | |
dc.identifier.uri | https://hdl.handle.net/11452/46760 | |
dc.identifier.volume | 34 | |
dc.identifier.wos | 000784492200001 | |
dc.indexed.wos | WOS.SCI | |
dc.language.iso | en | |
dc.publisher | Taylor & Francis Ltd | |
dc.relation.journal | Journal of Chemotherapy | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Infectious-diseases-society | |
dc.subject | Clinical-practice guidelines | |
dc.subject | Management | |
dc.subject | Mortality | |
dc.subject | Sepsis | |
dc.subject | Pneumonia | |
dc.subject | Diagnosis | |
dc.subject | Adults | |
dc.subject | Carbapenem resistance | |
dc.subject | Gram-negative pathogens | |
dc.subject | Septic shock | |
dc.subject | Oncology | |
dc.subject | Infectious diseases | |
dc.subject | Pathology | |
dc.subject | Pharmacology & pharmacy | |
dc.title | Carbapenem-resistant Gram-negative pathogens associated with septic shock: A review of 120 cases | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 73351d49-e518-4e6a-8f69-c922f8f24611 | |
relation.isAuthorOfPublication.latestForDiscovery | 73351d49-e518-4e6a-8f69-c922f8f24611 |