Publication: The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury running title: Haematologic parameters in paediatric head trauma
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Date
2022-05-26
Authors
Authors
Eser, Pınar
Corabay, Seniha
Özmarasali, Ali İmran
Ocakoğlu, Gökhan
Taşkapılıoğlu, Mevlut Özgür
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor
Abstract
Objective Analyzing the association between hematologic parameters and abnormal cranial computerized tomography (CT) findings after head trauma. Material and methods A total of 287 children with isolated traumatic brain injury (TBI) were divided into the 'normal' (NG), 'linear fracture' (LFG) and 'intraparenchymal injury' groups (IPG) based on head CT findings. Demographical/clinical data and laboratory results were obtained from medical records. Results The neutrophil-lymphocyte ratio was markedly higher in the LFG (p = 0.010 and p = 0.016, respectively) and IPG (p = 0.004 and p < 0.001, respectively) compared with NG. Lower lymphocyte-monocyte ratio (p = 0.044) and higher red cell distribution width-platelet ratio (RPR) (p = 0.030) were associated with intraparenchymal injuries. Patients requiring neurosurgical intervention had higher neutrophil-lymphocyte ratio (p = 0.026) and RPR values (p = 0.031) and lower platelet counts (p = 0.035). Lower levels of erythrocytes (p = 0.005), hemoglobin (p = 0.003) and hematocrit (p = 0.002) were associated with severe TBI and unfavorable outcome (p = 0.012, p = 0.004 and p = 0.006, respectively). Conclusions Hematologic parameters are useful in predicting the presence of abnormal cranial CT findings in children with TBI in association with injury severity; surgery need and clinical outcome.
Description
Keywords
Glasgow coma scale, Cell distribution width, To-lymphocyte ratio, Computed-tomography, Radiation-exposure, Motor score, Neutrophil, Mild, Anemia, Management, Glasgow coma score, Hematologic markers, Neurosurgery, Outcome, Pediatric patients, Traumatic brain injury, Science & technology, Life sciences & biomedicine, Neurosciences, Rehabilitation, Neurosciences & neurology