Publication:
The association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury running title: Haematologic parameters in paediatric head trauma

dc.contributor.authorEser, Pınar
dc.contributor.authorCorabay, Seniha
dc.contributor.authorÖzmarasali, Ali İmran
dc.contributor.authorOcakoğlu, Gökhan
dc.contributor.authorTaşkapılıoğlu, Mevlut Özgür
dc.contributor.buuauthorEser, Pınar
dc.contributor.buuauthorCorabay, Seniha
dc.contributor.buuauthorÖZMARASALI, ALİ İMRAN
dc.contributor.buuauthorOCAKOĞLU, GÖKHAN
dc.contributor.buuauthorTAŞKAPILIOĞLU, MEVLÜT ÖZGÜR
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Beyin Cerrahisi Anabilim Dalı
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı
dc.contributor.orcid0000-0003-0132-9927
dc.contributor.orcid0000-0002-7529-2808
dc.contributor.orcid0000-0002-1114-6051
dc.contributor.orcid0000-0001-5472-9065
dc.contributor.researcheridAAH-5180-2021
dc.contributor.researcheridAAI-2073-2021
dc.contributor.researcheridCAI-5927-2022
dc.contributor.researcheridEQP-8538-2022
dc.date.accessioned2024-09-26T07:29:23Z
dc.date.available2024-09-26T07:29:23Z
dc.date.issued2022-05-26
dc.description.abstractObjective Analyzing the association between hematologic parameters and abnormal cranial computerized tomography (CT) findings after head trauma. Material and methods A total of 287 children with isolated traumatic brain injury (TBI) were divided into the 'normal' (NG), 'linear fracture' (LFG) and 'intraparenchymal injury' groups (IPG) based on head CT findings. Demographical/clinical data and laboratory results were obtained from medical records. Results The neutrophil-lymphocyte ratio was markedly higher in the LFG (p = 0.010 and p = 0.016, respectively) and IPG (p = 0.004 and p < 0.001, respectively) compared with NG. Lower lymphocyte-monocyte ratio (p = 0.044) and higher red cell distribution width-platelet ratio (RPR) (p = 0.030) were associated with intraparenchymal injuries. Patients requiring neurosurgical intervention had higher neutrophil-lymphocyte ratio (p = 0.026) and RPR values (p = 0.031) and lower platelet counts (p = 0.035). Lower levels of erythrocytes (p = 0.005), hemoglobin (p = 0.003) and hematocrit (p = 0.002) were associated with severe TBI and unfavorable outcome (p = 0.012, p = 0.004 and p = 0.006, respectively). Conclusions Hematologic parameters are useful in predicting the presence of abnormal cranial CT findings in children with TBI in association with injury severity; surgery need and clinical outcome.
dc.identifier.doi10.1080/02699052.2022.2077442
dc.identifier.eissn1362-301X
dc.identifier.endpage749
dc.identifier.issn0269-9052
dc.identifier.issue6
dc.identifier.startpage740
dc.identifier.urihttps://doi.org/10.1080/02699052.2022.2077442
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/02699052.2022.2077442
dc.identifier.urihttps://hdl.handle.net/11452/45280
dc.identifier.volume36
dc.identifier.wos000799853400001
dc.indexed.wosWOS.SCI
dc.indexed.wosWOS.SSCI
dc.language.isoen
dc.publisherTaylor
dc.relation.journalBrain Injury
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGlasgow coma scale
dc.subjectCell distribution width
dc.subjectTo-lymphocyte ratio
dc.subjectComputed-tomography
dc.subjectRadiation-exposure
dc.subjectMotor score
dc.subjectNeutrophil
dc.subjectMild
dc.subjectAnemia
dc.subjectManagement
dc.subjectGlasgow coma score
dc.subjectHematologic markers
dc.subjectNeurosurgery
dc.subjectOutcome
dc.subjectPediatric patients
dc.subjectTraumatic brain injury
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectNeurosciences
dc.subjectRehabilitation
dc.subjectNeurosciences & neurology
dc.titleThe association between hematologic parameters and intracranial injuries in pediatric patients with traumatic brain injury running title: Haematologic parameters in paediatric head trauma
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication679713c1-5ac6-4cd5-8dae-bdc9e1656d96
relation.isAuthorOfPublication8ff963e8-284c-49e2-99b9-a46777690e8c
relation.isAuthorOfPublication5366e0c2-f020-4a2d-8d97-46928026680f
relation.isAuthorOfPublication.latestForDiscovery679713c1-5ac6-4cd5-8dae-bdc9e1656d96

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