Publication: Pulmonary sclerosing hemangioma exhibiting a high KI-67 proliferation index
Date
2012-04-17
Authors
Authors
Akyıldız, Elif Ülker
Bayram, Sami
Arıcı, Akgül
Kasap, Mehtap
Journal Title
Journal ISSN
Volume Title
Publisher
Erciyes Üniversitesi
Abstract
Pulmonary sclerosing hemangioma (PSH) is a rare pulmonary neoplasm. This tumour was originally thought to be a variant lesion of hemangioma. Today, however, it has been elucidated to be a tumour of epithelial origin derived from the primitive respiratory epithelium. Previous studies have reported a low Ki67 proliferation index in cases of pulmonary sclerosing hemangioma (1.4-2.2%). Moreover, the biological nature of this neoplasm, which rarely tends to metastasise to the lymph nodes, has yet to be thoroughly elucidated. A female patient in whom PSH exhibiting a high Ki-67 proliferation index was detected in the lung during follow-up for lymphoma is reported in the present study. While the Ki 67 proliferation index was 3-4% in some areas, it increased up to 15-20% in other areas. No recurrence or metastases were evident at postoperative follow-up.
Description
Keywords
Lung, Hemangioma, Sclerosing, Immunohisto-chemistry, General & internal medicine