Publication:
Morphometric shape analysis of corpus callosum in children with down syndrome

dc.contributor.authorGürsel, Başak Erdemli
dc.contributor.authorErcan, İlker
dc.contributor.authorŞahin, İbrahim
dc.contributor.authorÖngen, Gökhan
dc.contributor.buuauthorERDEMLİ GÜRSEL, BAŞAK
dc.contributor.buuauthorERCAN, İLKER
dc.contributor.buuauthorŞahin, İbrahim
dc.contributor.buuauthorÖNGEN, GÖKHAN
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentRadyolog Ana Bilim Dalı
dc.contributor.orcid0000-0002-2382-290X
dc.contributor.orcid0000-0002-0047-1780
dc.contributor.researcheridAAH-6568-2021
dc.contributor.researcheridHII-7787-2022
dc.contributor.researcheridABF-2367-2020
dc.contributor.researcheridJJO-9241-2023
dc.date.accessioned2024-09-30T06:03:34Z
dc.date.available2024-09-30T06:03:34Z
dc.date.issued2023-08-31
dc.description.abstractDown syndrome (DS) is characterized by varying degrees of mental retardation and delay in neurocognitive functions. Herein, we analyzed the morphometric shape of the corpus callosum (CC) in children with DS. Twenty-three DS cases underwent magnetic resonance imaging and have grossly normal CC, and 23 control group cases were included in this retrospective study (2012-2020). The CC was obtained from T2-weighted mid-sagittal images, and certain anatomical points were marked on the CC. Statistical geometric shapes and deformations of CC were evaluated for both groups. The age range of patients with DS and control group was 6 to 42 months. A statistically significant difference was found in the shape of CC between the groups (P < .001). Deformation was most evident in the splenium in the DS group.
dc.identifier.doi10.1177/00099228231196933
dc.identifier.endpage821
dc.identifier.issn0009-9228
dc.identifier.issue6
dc.identifier.startpage815
dc.identifier.urihttps://doi.org/10.1177/00099228231196933
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/00099228231196933
dc.identifier.urihttps://hdl.handle.net/11452/45455
dc.identifier.volume63
dc.identifier.wos001061755400001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.journalClinical Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBrain
dc.subjectMorphology
dc.subjectDown syndrome
dc.subjectCorpus callosum
dc.subjectSplenium
dc.subjectShape analysis
dc.subjectPediatrics
dc.titleMorphometric shape analysis of corpus callosum in children with down syndrome
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Radyolog Ana Bilim Dalı
local.contributor.departmentSağlık Bilimleri Enstitüsü/Biyoistatistik Ana Bilim Dalı
relation.isAuthorOfPublication67499dad-8aad-4b13-9547-dde1bfaf4441
relation.isAuthorOfPublication50e4dfdb-25cd-43af-94c9-464881669605
relation.isAuthorOfPublicationedae7686-a2e3-4d00-8b8b-76c9ab110f2d
relation.isAuthorOfPublication.latestForDiscovery67499dad-8aad-4b13-9547-dde1bfaf4441

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