Publication: Big data and reference intervals: Rationale, current practices, harmonization and standardization prerequisites and future perspectives of indirect determination of reference intervals using routine data
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Date
2021-03-10
Authors
Özarda, Yeşim
Authors
Martinez-Sanchez, Luisa
Marques-Garcia, Fernando
Blanco, Albert
Brouwer, Nannette
Canalias, Francesca
Cobbaert, Christa
Thelen, Marc
den Elzen, Wendy
Journal Title
Journal ISSN
Volume Title
Publisher
Walter De Gruyter Gmbh
Abstract
Reference intervals are commonly used as a decision-making tool. In this review, we provide an overview on "big data " and reference intervals, describing the rationale, current practices including statistical methods, essential prerequisites concerning data quality, including harmonization and standardization, and future perspectives of the indirect determination of reference intervals using routine laboratory data.
Description
Keywords
Laboratory reference limits, Reference values, Patient data, Recommendation, Bhattacharya, Blood, Plea, Big data, Indirect methods, Reference intervals, Science & technology, Life sciences & biomedicine, Medical laboratory technology