Publication: A report of 13 cases of merkel cell carcinoma: Single-center experience and review of the literature
Date
2019-06-01
Authors
Authors
Yazıcı, Serkan
Yazıcı, Elif Irmak
Adım, Şaduman Balaban
Başkan, Emel Bülbül
Aydoğan, Kenan
Sarıcaoğlu, Hayriye
Journal Title
Journal ISSN
Volume Title
Publisher
Korean Dermatological Assoc
Abstract
Background: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. Objective: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. Methods: Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved. Results: Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years. Conclusion: This is the first largest report from Turkish population with female predominance, and lower extremity tendency.
Description
Keywords
Epidemiology, Update, Skin, Polyomavirus, Biology, Cancer, Mechanoreceptor, Merkel cell, Merkel cell carcinoma, Neuroendocrine carcinoma, Pathogenesis, Prognosis, Trabecular carcinoma, Dermatology